Endocrine Abstracts

Background: Somatic and bi-allelic DICER1 mutations have been reported in subsets of sporadic thyroid tumors, affirming a clear involvement of this gene in the development of thyroid tumors. As a recent study has highlighted associations between DICER1 mutations and macrofollicular patterns, abortive changes, and papillary structures, we aimed to investigate these observations in a bi-institutional cohort.Methods: A total of 61 thyroid lesions (...