Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep996 | Pituitary - Clinical | ECE2017

Sheehan syndrome presenting 21 years later as severe heart failure

Ferreira Ana Goncalves , Alegria Sofia , Cordeiro Maria Carlos , Portugal Jorge

Introduction: Sheehan syndrome (SS) is caused by postpartum necrosis of the pituitary gland, associated with significant haemorrhage during or after delivery. It is rare in developed countries, but still frequent in underdeveloped ones. We present a rare presentation of this syndrome.Clinical case: A 48 years old black woman presented at the emergency department for long term fatigue and dyspnea that worsened a few days before. Her physical examination r...

ea0055wa13 | Workshop A: Disorders of the hypothalamus and pituitary (I) | SFEEU2018

Cushing’s disease relapse associated with central diabetes insipidus

Ferreira Ana , Silva Tiago , Bastos Filipa , Manita Isabel , Cordeiro Maria Carlos , Portugal Jorge

Introduction: Central diabetes insipidus (DI) is a frequent complication of transfenoidal surgery for Cushing’s disease (CD). It can be transient or, more infrequently, permanent. The most common mechanism results from surgical neurohypophyseal damage rather than local mass effect from the pituitary adenoma.Case report: A 40 years old woman was referred to our Endocrinology outpatient clinic at the beginning of 2015 for new onset hypertension, signi...

ea0063p1076 | Pituitary and Neuroendocrinology 3 | ECE2019

Prolactinoma – is there a relationship between T2W signal intensity in MRI and response to treatment with dopamine agonists?

Ferreira Ana , Oliveira Guilherme , Bastos Filipa , Carlos Cordeiro Maria , Duarte Julia , Portugal Jorge

Introduction: Prolactinomas are mostly benign tumours usually managed with pharmacological treatment. Some, however, seem to be resistant to dopamine agonists (DA) for unclear reasons. The relationship between T2W signal intensity (T2WSI) and response to treatment with somatostatin analogs is well described in acromegaly patients. Some evidence suggests that prolactinoma’s T2W hypointensity might be related to higher baseline prolactin levels and more resistance to DA.</p...

ea0063p1081 | Pituitary and Neuroendocrinology 3 | ECE2019

ACTH-positive diffuse idiopathic neuroendocrine cell hyperplasia (DIPNECH)

Ferreira Ana , Bastos Filipa , Pedro Paula , Lopes Miguel , Carlos Cordeiro Maria , Portugal Jorge

Introduction: DIPNECH is a preinvasive condition in which there is an idiopathic generalised proliferation of pulmonary neuroendocrine cells that can form tumourlets. There are very few cases described of ACTH secretion by these cells causing Cushing’s syndrome, some of them cyclic.Case report: A 41 year-old woman was sent to our Endocrinology outpatient clinic for menstrual disturbance, acne and excessive sweating. She had a recent diagnosis of DIP...

ea0049ep226 | Bone &amp; Osteoporosis | ECE2017

Cinacalcet for control of primary hyperparathyroidism: a single centre experience

da Silva Tiago Nunes , Ferreira Ana Goncalves , Cordeiro Maria Carlos , Matos Ana Catarina , Portugal Jorge

Although primary hyperparathyroidism (PHPT) is usually cured by surgery, some individuals are unable to undergo parathyroidectomy and are refractory to standard calcium lowering medical therapy. In such cases, targeted therapy with cinacalcet may be useful.The aim of this study was to access the short-term efficacy of cinacalcet in lowering calcium (Ca2+) levels in patients with PHPT unable to undergo parathyroidectomy and refractory to standa...

ea0020p533 | Paediatric Endocrinology | ECE2009

Prevalence of autoimmune thyroiditis in children with diabetes mellitus

Veloza Andreia , Coelho Catarina , Manita Isabel , Cordeiro Maria , Passos Dolores , Raimundo Luisa , Portugal Jorge

Introduction: Type 1 diabetes mellitus (DM1) is frequently associated with other autoimmune diseases. Among children and adolescents, thyroid disease is the most common autoimmune endocrinopathy. The possibility of occult thyroid disease should be considered at diagnosis and when a patient is assessed at the annual review.Objective: The aim of our study was to determine the prevalence of autoimmune thyroiditis among children and adolescents with type 1 d...

ea0063p990 | Diabetes, Obesity and Metabolism 3 | ECE2019

What is the factor that most influences perinatal outcomes in pregnant women with Gestational Diabetes Mellitus: Country of origin or previous Gestational Diabetes?

Ferrinho Catia , Matos Ana Catarina , Cordeiro Maria Carlos , Bastos Filipa , Ferreira Rute , Duarte Joao Sequeira , Oliveira Manuela , Portugal Jorge

Introduction: Gestational Diabetes Mellitus (GDM) is one of the pregnancy diseases with the highest rate of complications, influenced by several factors. Its prevalence has increased, with a prevalence of 7.2% in Portugal.Objective: Characterize pregnant women with GDM and evaluate the perinatal outcomes according to the country of origin and previous GDM.Material and methods: Cross-sectional and retrospective study. We collected c...

ea0049ep1298 | Thyroid (non-cancer) | ECE2017

The role of 99mTc-sestamibi in amiodarone-induced thyrotoxicosis – Case report

Victor Margarida , Ferreira Ana Goncalves , Carmona Susana , Luiz Henrique Vara , Cordeiro Maria Carlos , Portugal Jorge , Santos Ana Isabel

Introduction: Amiodarone is an antiarrhythmic iodine-rich drug, known to induce thyroid dysfunction both due to its high iodine content and through amiodarone-induced thyrotoxicosis (AIT), being this latter process classified into three different types. Type 1 is associated with increased thyroid hormone synthesis; type 2 is a destructive process with thyroid hormone release and type 3 is thought to be a mixture of the former two. Since treatment options are different, there h...

ea0037ep939 | Thyroid (non-cancer) | ECE2015

Seasonality in paediatric Graves' disease compared to the general population: impact of month of birth: a national study

da Silva Tiago Nunes , Pereira Bernardo Dias , Luiz Henrique Vara , Matos Ana Catarina , Cordeiro Maria Carlos , Raimundo Luisa , Portugal Jorge

Paediatric Graves’ disease (PGD) is an uncommon autoimmune disorder with a multifactorial origin. Although, in some autoimmune endocrinophaties the seasonality of month of birth (MOB) distribution differed from the general population, this association has not been study in PGD. The aim of this work was to analyse the impact of seasonality of MOB on PGD incidence in Portugal.In 2013, the Portuguese Paediatric Society of Diabetes and Endocrinology und...

ea0014p480 | (1) | ECE2007

Bartter syndrome – a case of secondary hyperaldosteronism

Manita Isabel , Veloza Andreia , Coelho Catarina , Saraiva Catarina , Passos Dolores , Cordeiro Maria , Raimundo Luísa , Portugal Jorge

Introduction: Bartter syndrome represents a set of closely related autosomal recessive renal tubular disorders characterised by hypokalemia, hypochloremia, metabolic alkalosis and hyperreninemia with normal blood pressure. The underlying abnormality results in excessive urinary losses of sodium, chloride and potassium. Bartter syndrome is classified into 3 main clinical variants: neonatal Bartter syndrome, classic syndrome and Gitelman syndrome.Case repo...