Endocrine Abstracts

Introduction: Fine-needle aspiration cytology (FNAC) of thyroid nodules can be associated with non-diagnostic (ND) results, despite the usage of ultrasound (US) guidance. It is recommended to repeat the FNAC because of the possible risk of malignancy in these nodules.Aim: To evaluate the influence of demographic, clinical and echographic characteristics in the recurrence of ND FNAC in a thyroid nodule.Methods: Retrospective review ...

Background: Chordomas are rare, invasive and slow growing bone tumours with different locations. Parasellar chordomas are even more rare and the initial manifestations include visual and/or neurological symptoms. In addition, endocrine dysfunction may be present. We describe 4 cases of parasellar chordomas.Clinical cases: 1) Female, 55-years-old, reported headache associated with restriction of left eye movement for the past 3 months. Brain magnetic reso...

Background: Denosumab (Dmab) is a human monoclonal antibody with an anti-reabsorptive bone effect, used in osteoporosis treatment. It is also suggested that Dmab may improve glucose tolerance through the reduction of hepatic insulin resistance. Some studies have suggested that insulin sensitivity and glycemia can influence bone metabolism.Aims: To evaluate the relationship between bone turnover markers (BTM) and insulin resistance and glycemia in fractur...

Introduction: Almost all type 1 diabetes mellitus (T1DM) patients have autoantibodies (ab) at disease onset. These ab prevalence varies according to patients’ age, origin and disease duration.Aim: Determine diabetes mellitus ab prevalence in a paediatric and adult T1DM Portuguese according to their age on diagnosis, gender and diabetes duration.Methods: Retrospective review of T1DM ab (glutamic acid decarboxylase 65 autoantibo...

Background: The effect of maternal weight gain in obstetric and perinatal morbidity in pregnant with gestational diabetes (GD) is not established.Objectives: Evaluation of the impact of weight gain in obstetric and perinatal outcomes in women with GD.Methods: Retrospective study of women with GD between January/2020-March/2021. Weight gain in pregnancy was evaluated by 2009 IOM recommendations, women were divided in 3 groups: exces...