Endocrine Abstracts

Background: Recent reports have suggested a link between the thyroid hormone (TH) signalling pathway and liver disease, including hepatocellular carcinoma (HCC). Deiodinases are enzymes responsible for the peripheral metabolism of TH. Although the expression of deiodinases type 1 (D1) and 3 (D3) has been shown to change during induced liver injury, their role in hepatocarcinogenesis is still poorly understood.Aims: To evaluate the role of deiodinases and...