Searchable abstracts of presentations at key conferences in endocrinology

ea0056oc8.2 | MicroRNAs as biomarkers in endocrine diseases | ECE2018

MicroRNA expression profiling and functional annotation analysis of their targets in patients with diabetic kidney disease

Assmann Tais Silveira , Recamonde-Mendoza Mariana , Costa Aline , Punales Marcia , Tschiedel Balduino , Canani Luis Henrique , Bauer Andrea Carla , Crispim Daisy

Context: Diabetic kidney disease (DKD) is a common microvascular complication that affects approximately 40% of patients with diabetes mellitus (DM). This complication is the leading cause of end-stage renal disease (ESRD) in patients starting renal replacement therapy and is associated with increased cardiovascular mortality. Although a tight glycemic control is able to reduce the development and delay the progression of DKD, current therapies are still not totally effective ...