Searchable abstracts of presentations at key conferences in endocrinology

ea0032p927 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Therapeutic response to recombinat somatropin in children with isolated deficiency of GH

Belo Sandra , Nogueira Claudia , Corujeira Susana , Costa Carla , Castro-Correia Cintia , Fontoura Manuel

Introduction: Generously supported by IPSEN)-->Treatment with recombinant ST is subject to strict criteria. Differences in the response to therapy based on the maximum level of ST in diagnostic tests (ST ≤5 vs ST >5 ng/ml), could predict whose patients would benefit more from therapy.Purpase: Assess differences in the response to therapy with rST in patients with IDGH.Methods: S...

ea0090ep926 | Reproductive and Developmental Endocrinology | ECE2023

Growth hormone treatment in SGA children leads to worsening of insulin resistance parameters without beneficial effects on lipid profile – a 3-year retrospective study

Silva Maria , Sergio Neves Joao , Costa Carla , Santos Silva Rita , Ferreira Sofia , Carvalho Davide , Castro-Correia Cintia

Background: Children who were born small for gestational age (SGA) and who do not have adequate catch-up growth until 4 years old have indication for treatment with recombinant human growth hormone (rhGH). The metabolic consequences of this treatment are relatively unknown. Objective: To evaluate the effect of rhGH treatment on insulin sensitivity and lipid profile.Materials and methods: A retrospective observational study of child...

ea0041gp142 | Paediatric Endocrinology &amp; Development | ECE2016

Association between urinary magnesium and glycaemic control in children and adolescents with type 1 diabetes mellitus

Cunha Filipe , Oliveira Juliana , Saavedra Ana , Alves Ines , Santos-Silva Rita , Costa Carla , Castro-Correia Cintia , Fontoura Manuel

Background: Hypomagnesemia is common in patients with diabetes; possibly due to higher renal magnesium excretion in those patients. Hypomagnesemia seems to correlate with poor glycaemic control. The relationship between urinary magnesium (UMg) and glycaemic control is not known. We aimed to study the association between UMg and glycaemic control in a type 1 diabetes (T1D) pediatric population.Methods: Study of a pediatric population with T1D attending th...

ea0073ep178 | Reproductive and Developmental Endocrinology | ECE2021

Precocious puberty: two siblings, two diagnosis

Maria João Ferreira , Moita Rita , Ferreira Sofia , Costa Carla , Santos Silva Rita , Cíntia Castro-Correia

8-year-old girl is referred to a Pediatric Endocrinologist for the appearance of thelarche, first noted at 6.5 years. She had a relevant clinical history of a neonatal meningitis, requiring prolonged hospitalization and the need for ventriculoperitoneal shunt. On physical examination, she had breast development and dark, coarse pubic hair compatible with Tanner stage 3. She weighed 32.3 kg (percentile – Pc- 75–90), her height was 128 cm (Pc 50) and her annual growth ...

ea0073aep69 | Adrenal and Cardiovascular Endocrinology | ECE2021

Quality of life in children diagnosed with non-classic congenital adrenal hyperplasia

Maria João Ferreira , Moita Rita , Borges-Canha Marta , Silva Rita Santos , Ferreira Sofia , Costa Carla , Carvalho Davide , Cíntia Castro-Correia

IntroductionNon-classical congenital adrenal hyperplasia (NC-CAH) is a chronic disease characterized by excessive androgen production. Affected children may have their quality of life negatively affected by the awareness of a medical condition, symptoms of hyperandrogenism and the burden of daily medication administration. Pediatric Quality of Life Inventory 4.0 (PedsQL) is a validated tool to assess health-related QoL (HRQoL).Meth...