Searchable abstracts of presentations at key conferences in endocrinology

ea0099p489 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Diabetes remission after bariatric surgery: a 10-years follow-up study

Meira Ines , Menino Joao , Goncalves Juliana , Ferreira Helena , Rita Leite Ana , Ferreira Patricia , Ribeiro Sara , Moreno Telma , Silva Diana , Freitas Paula , Lima da Costa Eduardo , Queiros Joana

Introduction: Although lifestyle measures and medical therapy are the cornerstone of type 2 diabetes (T2DM) management, achieving optimal glycemic control in T2DM patients with obesity remains challenging. There is strong and consistent evidence that bariatric surgery (BS) is an effective strategy to improve glycemia in diabetic patients and often leads to remission of T2DM in patients with obesity. The majority of the published literature supporting T2DM remission after BS ha...

ea0081p3 | Adrenal and Cardiovascular Endocrinology | ECE2022

Long-term cardiometabolic morbidity in young adults wWith classic 21-hydroxylase deficiency congenital adrenal hyperplasia

Righi Beatrice , Rashid Ali Salma , Bryce Jillian , Tolinson Jeremy , Bonfig Walter , Baronio Federico , Costa Eduardo C , Guaragna-Filho Guilherme , T'Sjoen Guy , Cools Martine , Markosyan Renata , A S S Bachega Tania , C Miranda Mirela , Iotova Violeta , Falhammar Henrik , Ceccato Filippo , Daniel Eleni , Auchus Richard , Ross Richard , Ahmed Faisal

Background: Congenital adrenal hyperplasia (CAH) and long-term glucocorticoid treatment may be associated with an increased risk of developing cardiometabolic sequelae such as abnormal glucose homeostasis, hyperlipidaemia, hypertension, cardiovascular (CV) disease, obesity and osteoporosis.Objectives: To study the current practice amongst expert centres for assessing cardiometabolic outcomes in adult patients with 21-hydroxylase CAH and to assess the pre...

ea0090ep286 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Prediabetes remission after bariatric surgery: A 4-years follow-up study

Borges-Canha Marta , Neves Joao Sergio , Silva Maria , Mendonca Fernando , Moreno Telma , Ribeiro Sara , Vale Catarina , Goncalves Juliana , Ferreira Helena Urbano , Santos Sara , Calheiros Raquel , Meira Ines , Menino Joao , Guerreiro Vanessa , Pedro Jorge , Varela Ana , Souto Selma , Lima da Costa Eduardo , Freitas Paula , Carvalho Davide , Group CRIO

Background: Bariatric surgery leads to weight loss and to cardiometabolic risk improvement. Although prediabetes remission after bariatric surgery is biologically plausible, data on this topic is scarce.Aim: We aimed to access pre-diabetes remission rate and clinical predictors of remission in a 4 year follow up period.Methods: Observational longitudinal study including patients with morbid obesity and prediabetes submitted to bari...

ea0078p1 | Adrenal | BSPED2021

Analysis of therapy monitoring in the International Congenital Adrenal Hyperplasia Registry

Lawrence Neil , Bacila Irina , Dawson Jeremy , Bryce Jillian , van den Akker Erica , Sartori Sanchez Bachega Tania Aparecida , Baronio Federico , Birkebaek Niels Holtum , Bonfig Walter , Claahsen Hedi , Correa Costa Eduardo , Devries Liat , Elsedfy Heba , Guven Ayla , Hannema Sabine , Iotova Violeta , van der Kamp Hetty J , Clemente Leon Maria , Lichiardopol Corina Raducanu , Milenkovic Tatjana , Neumann Uta , Nordenstrom Ana , Poyrazoglu Sukran , Probst-Scheidegger Ursina , De Sanctis Luisa , Thankamony Ajay , Vieites Ana , Yavas Zehra , Ahmed Faisal , Krone Nils

Background: Congenital Adrenal Hyperplasia (CAH) requires exogenous steroid replacement and can be monitored with 17-OH Progesterone and Androstenedione. We reviewed real world data to evaluate these markers in relation to hydrocortisone dose in patients treated in 21 centres throughout 14 countries.Method: Retrospective cohort study using pseudonymised data from patients with 21α-Hydroxylase Deficiency recorded in the International Congenital Adren...

ea0066oc1.1 | Oral Communications 1 | BSPED2019

Exploring trends in the glucocorticoid and mineralocorticoid treatment of congenital adrenal hyperplasia by analysing data from the I-CAH registry

Bacila Irina-Alexandra , Blankenstein Oliver , Neumann Uta , Grinten Heidi L Claahsen-van der , Krone Ruth , Bachega Tania SS , Miranda Mirela C , Mendonca Berenice , Birkebaek Niels H , Cools Martine , Milenkovic Tatjana , Bonfig Walter , Tomlinson Jeremy W , Elsedfy Heba , Balsamo Antonio , Ortolano Rita , Hannema Sabine , Higham Claire , Atapattu Navoda , Lichiardopol Corina , Guran Tulay , Abali Zehra , Mohnike Klaus , Finken Martijn JJ , Vieites Ana , Darendeliler Feyza , Guven Ayla , Korbonits Marta , Vries Liat de , Costa Eduardo , Einaudi Silvia , Kamp Hetty van der , Iotova Violeta , Ross Richard , Ahmed S Faisal , Krone Nils

Introduction: There is no unified approach in clinical practice regarding the medical management of congenital adrenal hyperplasia (CAH), despite existent international guidance. We aimed to explore geographical and temporal variations in the treatment with glucocorticoids and mineralocorticoids of patients with CAH.Methods: We collected data recorded by 33 centres from 16 countries in the I-CAH Registry. We analysed patient visits between 1982 and 2018,...

ea0103oc5.5 | Endocrine Oral Communications 1 | BSPED2024

Glucocorticoid replacement therapy in congenital adrenal hyperplasia and its associations with growth outcomes - real world data analysis from an international cohort of 1500 patients

A Bacila Irina , Lawrence Neil R. , Balagamage Chamila , Bryce Jillian , Ali Salma R. , Alimussina Malika , Chen Minglu , Arya Ved Bhushan. , Atapattu Navoda , Bachega Tania , Barat Pascal , Baronio Federico , Bertelloni Silvano , Birkebaek Niels , Bonfig Walter , Bruin Christiaan de. , - van der Grinten Hedi Claahsen. , Cools Martine , Costa Eduardo , Crowne Elizabeth , Davies Justin H. , Debono Miguel , Vries Liat de. , Kubat Katja Dumic. , Elsedfy Heba , Evliyaoglu Olcay , Flueck Christa , Gazdagh Gabriella , German Alina , Gevers Evelien F. , Globa Evgenia , Guran Tulay , Guven Ayla , Guazzarotti Laura , Hannema Sabine , Hatipoglu Nihal , Janus Dominika , Kamp Hetty van. de. , Karabouta Zacharoula , Krone Ruth E. , Leka-Emiri Sofia , Taube Nina Lenherr. , Lichiardopol Corina , Hassan Mona Mamdouh. , Marginean Otilia , Markosyan Renata , Mazen Inas , Miles Harriet , Mitchell Anna L. , Mohnike Klaus , Neumann Uta , Niedziela Marek , Nordenstrom Anna , O'Connell Susan M. , Phan-Hug Franziska , Poyrazoglu Sukran , Probst-Scheidegger Ursina , Rey Rodolfo , Russo Gianni , Salerno Mariacarolina , Sanctis Luisa de. , Seneviratne Sumudu N. , Segev-Becker Anat , Shenoy Savitha , Skae Mars , Thankamony Ajay , Ucar Ahmet , Utari Agustini , Vieites Ana , Wasniewska Malgorzata , Ahmed S Faisal. , Krone Nils P.

Background and Aim: Previous research using data from the I-CAH registry showed wide variation between countries in the provision of glucocorticoid (GC) replacement in congenital adrenal hyperplasia (CAH). In this study, we aimed to establish the impact of different GC doses on height and weight in children and young people with CAH.Methods: Data from children with CAH recorded in the I-CAH registry since 2003 was collected, providing a cohort of 1522 pa...