Searchable abstracts of presentations at key conferences in endocrinology

ea0053cd1.2 | Case Discussions: complex clinical cases 1.0 | OU2018

The clinical course of obesity in a patient with missed Cushing’s disease following Roux-en-Y gastric bypass then trans-sphenoidal surgery

Crane James

Case History: A 26 year old female underwent Roux-en-Y gastric bypass (RYGB) surgery for intractable peptic ulcer disease on a background of obesity. She had a history of 40kg weight gain over 8 years (weight 123 kg, BMI 41.1 kg/m2), hypertension, depression, insomnia and newly diagnosed type 2 diabetes. Following surgery, weight loss was disappointing (nadir 112 kg, −11 kg, −8.9%TBW, −22.9%EBW, BMI 37.5 kg/m2) and diabetes and hypertens...

ea0050ep091 | Obesity and Metabolism | SFEBES2017

The importance of the lows, and not the just the highs, of glycaemia in critical illness

Crane James , Rafique Shaina

Stress hyperglycaemia is a widely recognised feature of critical illness. Spontaneous hypoglycaemia, by contrast, is an underappreciated but serious complication. Here I present three cases encountered over 12 months in a single teaching hospital.Case 1: 59 year old female. Admitted with fever and leg pain. Cellulitis diagnosed and antibiotics commenced. Hours later, she became unresponsive and shocked, with evident necrotisi...

ea0050ep091 | Obesity and Metabolism | SFEBES2017

The importance of the lows, and not the just the highs, of glycaemia in critical illness

Crane James , Rafique Shaina

Stress hyperglycaemia is a widely recognised feature of critical illness. Spontaneous hypoglycaemia, by contrast, is an underappreciated but serious complication. Here I present three cases encountered over 12 months in a single teaching hospital.Case 1: 59 year old female. Admitted with fever and leg pain. Cellulitis diagnosed and antibiotics commenced. Hours later, she became unresponsive and shocked, with evident necrotisi...

ea0031p377 | Thyroid | SFEBES2013

Too low, too high: is it the Roux-en-Y? Fluctuating thyroid function post obesity surgery

Crane James , Scobie Ian

Hypothyroidism is common condition with a strong female preponderance and a UK prevalence of ~2%. It is normally treated with replacement oral levothyroxine.Morbid obesity is a costly public health issue with a prevalence in England of ~3% with two-thirds of sufferers being female. Weight loss surgery is increasingly employed as a successful and cost effective intervention for super-morbidly obese patients (BMI >40 kg/m2) in accordance wit...

ea0048oc6 | Oral Communications | SFEEU2017

Complexities cause considerable confusion in confirming a case of Cushing’s (after gastric bypass surgery)

Crane James , Wierzbicki Anthony , Ramachandran Radha , McGowan Barbara

Case history: A 26 year old female with severe gastro-oesophageal reflux disease was seen in our service for assessment prior to roux-en-Y gastric bypass (RYGB) surgery for this condition. She had additional history of obesity, hypertension, insomnia, cholecystectomy for gallstones and anxiety-depression. At age 18 her weight was 85 kg, BMI 28 kg/m2. She gained 40 kg over the subsequent 8 years and in clinic was 123 kg, BMI 41.1 kg/m2 with a gynaecoid pat...

ea0048p4 | Poster Presentations | SFEEU2017

Night-blindness and neurological sequelae post bariatric surgery

Iftikhar Mawara , Waller Kathryn , Crane James , McGowan Barbara

Background: Bariatric surgery is considered the most effective tool to manage the growing pandemic of obesity related health disorders. Lack of regular surveillance following bariatric procedures can put patients at risk of developing serious micro-nutritional deficiencies and related complications.Case report: A 51-year-old lady presented to the bariatric services in 2015 with long standing neurological symptoms including memory and cognitive impairment...

ea0025p327 | Thyroid | SFEBES2011

Management of hyperfunctioning thyroid malignancy with psychiatric co-morbidity

Till David , Gilbert Jackie , Lewis Dylan , Crane James , Aylwin Simon , McGregor Alan

A 70-year-old female with known schizophrenia presented in hyperthyroid crisis. Examination revealed muscle wasting, tremor, sweating, low-grade fever, and sinus tachycardia. Biochemistry confirmed the diagnosis (TSH <0.1 mlU/l, thyroxine 41 pmol/l (9–25), tri-iodothyronine 25 pmol/l (3.5–6.5)). The patient was commenced on i.v. esmolol and carbimazole (40 mg) crushed into warm milk.However, lacking mental capacity, and refusing to take all...