ea0003oc6 | Genetics: New Insights into Endocrine Disease | BES2002
Strahorn P
, Graham D
, Crawford L
, Morton J
, Sattar N
, Dominiczak A
Objective: The spontaneously hypertensive stroke prone rat (SHRSP) is a model of insulin resistance and dyslipidemia. Feeding a 60% fructose diet exaggerates these phenotypes. It has been suggested that the Y chromosome may influence lipid levels in the spontaneously hypertensive rat (SHR). Therefore we examined the effects of Y chromosome on lipid phenotypes in the SHRSP after fructose feeding.Design and Methods: The S.W. Y consomic strain was construc...