Searchable abstracts of presentations at key conferences in endocrinology

ea0022p118 | Bone/Calcium | ECE2010

Primary hyperparathyroidism diagnosis – new insights of an old dilemma

Vulpoi Carmen , Stefanescu Cipriana , Ionescu Lidia , Crumpei Felicia , Vasiliu Ioana , Balcan Roxana , Idriceanu Jeanina , Mogos Voichita

Primary hyperparathyroidism (PHPT) is a relatively frequent problem in clinical endocrine practice. Minimally invasive parathyroid surgery is the treatment of choice but requires precise preoperatory localization. The most commonly investigation methods are ultrasonography and scintigraphy, but they are not always diagnostic. PTH assay of the aspirate from an ultrasound-guided fine-needle aspiration (USFNA) may confirm the location of pathological parathyroid tissue. The aim o...

ea0022p442 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

The laterocervical unique masses – a challenging pathology

Anca-Roxana Costan , Carmen Vulpoi , Carmen Vicol , Felicia Crumpei , Dan Ferariu , Eugenia Popescu , Victor-Vlad Costan

Introduction: Extrathyroidal unique laterocervical masses are infrequent, and their etiological diagnosis is difficult. Since clinical and imagistic features cannot distinguish between different ethiologies, morphological data are mandatory in order to establish a precise therapeutic strategy. Therefore the initial treatment is surgery, followed by an adequate therapeutical scheme. We would like to report our experience treating this pathology.Patients a...

ea0049ep188 | Endocrine tumours and neoplasia | ECE2017

An elevated chromogranin A: is it always a tumor progression?-case report

Bursuc Anamaria , Daniela Belceanu Alina , Armasu Ioana , Tirnovan Mirela , Manolachie Adina , Crumpei Felicia , Ciobanu Delia , Leustean Letitia , Vulpoi Carmen

Introduction: Pancreatic neuroendocrine tumors (PNET) are rare, with an incidence of 1/100,000/year. Chromogranin A (CgA) is the most valuable marker in the diagnosis and monitoring of PNET. One of the disadvantages is its low specificity and the existence of a number of processes leading to an increase in its concentration, which often results in confusion and diagnostic difficulties.Case report: We present a 44-years-old female patient...

ea0049ep792 | Endocrine tumours and neoplasia | ECE2017

Chronic stress and somatotroph axis in breast cancer more than a simple association

Crumpei Iulia , Armasu Ioana , Danciu Mihai , Tofan Mariana , Volovat Constantin , Belceanu Alina , Crumpei Felicia , Adomnicai Valentina , Vulpoi Carmen

Introduction: Epidemiological and clinical studies have proven direct correlations between chronic stress, inflammation and cancer progression. The inflammatory environment preexisting the malignant change and elevated IGF-1 levels are associated with higher cancer risk, especially through GH effects on cell proliferation and inhibition of apoptosis.Aim: To evaluate the relationship between biological and hormonal stress markers, growth factors and breas...

ea0041ep945 | Pituitary - Clinical | ECE2016

Sudden global health impairment in a male patient– could it be hypohysitis?

Bursuc Anamaria , Belceanu Alina Daniela , Armasu Ioana , Constantinescu Georgiana Andreea , Esanu Anda , Manciuc Carmen , Crumpei Felicia , Vulpoi Carmen

Introduction: Hypophysitis is a chronic inflammatory condition of the pituitary gland which typically presents with hypopituitarism and a pituitary mass. The disease is rare, with an estimated incidence of 1/9000000. Most reported cases are in women during peripartum period and only approximately 15% of reported cases occur in males.Case report: Male patient, aged 57, smoker, with a history of hypertension, just returned from India, presented with anorex...

ea0037ep80 | Adrenal cortex | ECE2015

Metabolic abnormalities in patients with nonfunctional adrenal incidentaloma: random or causal?

Belceanu Alina Daniela , Armasu Ioana , Cirdei Oana , Crumpei Felicia , Preda Cristina , Leustean Letitia , Ungureanu Didona , Mogos Voichita , Vulpoi Carmen

Introduction: With a prevalence of 0.5–2% in computed tomography series, incidentally diagnosed nonfunctional adrenal tumours (NAI) become more and more common in clinical practice. It is not clear if the higher frequency of NAI in patients with metabolic syndrome is causal or random.Patients and methods: We retrospectively analysed patients diagnosed with adrenal tumors on computed tomography in 1 year interval (January–December 2014). Includi...

ea0037ep1301 | Clinical Cases–Thyroid/Other | ECE2015

Late onset of a rare autoimmune association: coeliac disease and Hashimoto's thyroiditis: hormonal and metabolic implications

Puiu Mirela , Popa Radu , Gologan Elena , Crumpei Felicia , Armasu Ioana , Vasiliu Ioana , Manolachie Adina , Preda Cristina , Vulpoi Carmen

Introduction: Several autoimmune determinations have been reported in association with autoimmune thyroidits (AIT). While the classical correlations with other endocrine or general autoimmune diseases like pernicious anemia or vitiligo are frequent and well defined, there are fewer data on other rarer associations, as with celiac disease (CD). In the absence of typical clinical symptoms this association may be overlooked, as in the case we present.Case p...

ea0035p592 | Endocrine tumours and neoplasia | ECE2014

Pancreatic neuroendocrine tumour with a silent long evolution: case report

Manolachie Adina , Crumpei Felicia , Volovat Constantin , Bodescu Ioana , Idriceanu Jeanina , Vasiliu Ioana , Fadur Alina , Preda Cristina , Vulpoi Carmen

Pancreatic neuroendocrine tumors (pNET) represent 1.3% of pancreatic tumours, ~65% patients presenting with metastatic/unresectable disease. Clinically, pNET may be asymptomatic, accompanied by carcinoid syndrome or abdominal pain.Patient N.A. aged 73, with a history of hemorrhagic pancreatitis, was diagnosed in 2003 with a hyperechoic heterogeneous solid pancreatic tumour of 28/28 mm. No therapy/monitoring were proposed. After 7 years of asymptomatic ev...