Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep215 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2016

TNF related apoptosis inducing ligand (TRAIL) reduces reactive oxygen species production by human aortic endothelial cells exposed to inflammatory stimuli

Forde Hannah , Davenport Colin , Rochfort Keith , Cummins Philip , Smith Diarmuid

Introduction: Accumulating evidence suggests that one of the most significant contributors to endothelial dysfunction is increased oxidative stress. Excessive reactive oxygen species (ROS) generation can have injurious effects within the vasculature including elevated expression of adhesion molecules, stimulation of vascular smooth muscle cell proliferation, and promotion of endothelial cell apoptosis; events which culminate in the formation and progression of atherosclerotic ...