Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1258 | Thyroid (non-cancer) | ECE2017

Fluctuating thyroid hormones in Graves disease: a case series of brittle Graves

Cuneyt Bilginer Muhammet , Faki Sevgul , Aydin Cevdet , Ozdemir Didem , Ali Tam Abbas , Ersoy Reyhan , Cakir Bekir

Introduction: Brittle hypertyroidism is a term used for the clinical situation characterized by hypo-hyperthyroidism with antithyroid drugs, despite good compliance and follow-up. Here, we presented five patients suggested to have Brittle Graves.Case-1: Thyrotoxicosis was observed in a 57-year-old female patient and Graves was diagnosed after laboratory and imaging examinations 25 months after initiation of propylthiouracil 50 mg/day, she developed hypot...

ea0056p1081 | Thyroid (non-cancer) | ECE2018

Coincidental prolactinoma and parathyroid adenoma in a patient with negative MEN1 and MEN4

Faki Sevgul , Aydin Cevdet , Cuneyt Bilginer Muhammet , Yukselguler Bagdegul , Abbas Tam Ali , Kilic Mehmet , Cakir Bekir

Introduction: Multiple endocrine neoplasia type 1 (MEN 1) is associated with neoplasia and hyperfunction of the parathyroid and pituitary glands, pancreatic islet cells, and neuroendocrine cells of the gut. Many authors advocate routine subtotal or total parathyroidectomy and autotransplantation for these patients. Here we demostrate negative MEN1 and MEN4 gene mutation analysis in a case with prolactinoma and a large parathyroid adenoma that could not be localized with preope...

ea0056p1155 | Thyroid cancer | ECE2018

Are there any differences between hot and cold nodules according to cytology and histopathology results?

Baser Husniye , Topaloglu Oya , Cuneyt Bilginer Muhammet , Ulusoy Serap , Kilicarslan Aydan , Ozdemir Elif , Ersoy Reyhan , Cakir Bekir

Introduction: Many recent studies have shown that detection of an incidental thyroid cancer among patients operated for a toxic thyroid disease is not infrequent. We aimed to compare cytology and histopathology results of cold, warm and hot nodules in patients who had thyroidectomy due to toxic multinodular goiter (TMNG).Methods: The cytology, histopathology and scintigraphy records of 1069 thyroid nodules from 413 patients who had operation with TMNG we...

ea0073aep675 | Thyroid | ECE2021

Multiple endocrine neoplasia type 2a (men 2a) case with bilateral medullary thyroid carcinoma and papillary thyroid carcinoma presentation

Suat Demir Ahmet , Tufekci Damla , Emur Gunay Yasemin , Coskun Hulya , Ucuncu Ozge , Cuneyt Bilginer Muhammet , Nuhoglu Irfan , Kocak Mustafa

IntroductionMEN 2A is an autosomal dominant disease, a familial syndrome with a mutation at RET proto-oncogene. %25 of medullary thyroid carcinoma (MTC) is a part of MEN 2A. Herein, we presented a patient with MEN 2A who was found to be heterozygos for RET mutation cause of the association of MTC and papillary thyroid carcinoma (PTC) is very rare.Case63 year old patient was admitted to the endocrinology clini...

ea0073ep73 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Case of Mucopolisaccharidosis Type 4A (Morquio 4A)

Suat Demir Ahmet , Emur Gunay Yasemin , Tufekci Damla , Nuhoglu Irfan , Coskun Hulya , Ucuncu Ozge , Cuneyt Bilginer Muhammet , Kocak Mustafa

IntroductionMucopolysaccharidosis type 4A (Morquio 4A) is an autosomal recessive lysosomal storage disease caused by a mutation in the gene encoding galactosamine 6 sulphatase (GALNS). ItÂ’s main clinical features include short stature, skeletal dysplasia, cloudy cornea, hearing loss and dental anomalies. Herein, a case of Morquio 4A, a rare cause of short stature is presented.Case reportA 41 year old fem...

ea0073ep221 | Thyroid | ECE2021

NIvolumab induced grade 3 hypothyroidism – case series

Cuneyt Bilginer Muhammet , Emur Gunay Yasemin , Tufekci Damla , Suat Demir Ahmet , Coskun Hulya , Nuhoglu Irfan , Ucuncu Ozge , Kocak Mustafa

IntroductionImmunological side effects related with use of immune checkpoint inhibitors (ICIs) are named as immune-related adverse events (irAEs). irAEs include clinical pictures such as autoimmune thyroiditis, hypophysitis, primary adrenal insufficiency and autoimmune diabetes mellitus. Nivolumab is an anti-PD-1 (anti-programmed cell death-1) monoclonal antibody approved for the treatment of malignant melanoma, advanced non-small cell lung cancer and ad...

ea0073aep724 | Thyroid | ECE2021

Post-operative resistant hypothyroidism of Graves’ disease patient resistant to anti-thyroid treatment

Emur Gunay Yasemin , Tufekci Damla , Ahmet Suat Demır , Cuneyt Bilginer Muhammet , Coskun Hulya , Nuhoglu Irfan , Ucuncu Ozge , Kocak Mustafa

IntroductionGravesÂ’ Disease resistance to anti-thyroid treatment and poor treatment compliance with levothyroxine treatment (pseudomalabsorption) are not common conditions. We presented this case because of the inability to provide euthyroidism with anti-thyroid treatment before the surgery and with levothyroxine after the surgery in the same patient.Case ReportA 24-year-old female patient was admitted w...

ea0073ep4 | Adrenal and Cardiovascular Endocrinology | ECE2021

Successful spontaneous pregnancy and successful delivery in a patient with severe 11-beta hydroxylase deficiency

Suat Demir Ahmet , Şafak akın , Tufekci Damla , Emur Gunay Yasemin , Cuneyt Bilginer Muhammet , Ucuncu Ozge , Coskun Hulya , Nuhoglu Irfan , Kocak Mustafa

Objective11-Beta Hydroxylase deficiency (11ß0HD) is a rare form of congenital adrenal hyperplasia, resulting in glucocorticoid deficiency, virilization and hypertension. In the literature, there are rare case reports of successful pregnancy in a patient with genetically confirmed classic 11ß0HD.CaseOur patient, now age 31, was diagnosed at birth with ambiguous genitalia. There was no family history ...

ea0073ep53 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Evaluation of the effect of lockdown order during Covid-19 pandemic on the clinical and metabolic parameters of obese patients in Turkey

Tufekci Damla , Coskun Hulya , Unal Egemen , Emur Gunay Yasemin , Suat Demir Ahmet , Cuneyt Bilginer Muhammet , Ucuncu Ozge , Nuhoglu Irfan , Kocak Mustafa

AimLockdown order during COVID-19 pandemic caused a sedentary life-style and disruptions in eating and sleeps patterns of obese patients. In this study, it is planned to evaluate the clinical and metabolic effects of this period on obese patients.MethodsThis study included 44 obese patients who were followed up in Endocrinology and Metabolic Diseases Clinic of Karadeniz Technical University. In this study, me...

ea0073ep110 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Ketosis-prone diabetes presenting with an atypical phenotype (A + /β + )

Tufekci Damla , Emur Gunay Yasemin , Ahmet Suat Demır , Cuneyt Bilginer Muhammet , Coskun Hulya , Nuhoglu Irfan , Ucuncu Ozge , Kocak Mustafa

IntroductionIn clinical practice, differentiating between the types of diabetes is not always possible. In recent years, there has been an increase in the cases of Type 2 diabetes triggered by diabetic ketoacidosis in young-adult age individuals, and this condition is known as ketosis-prone diabetes (KPD). In this report, we present a case of autoantibody-positive KPD who had an adequate pancreatic reserve and an atypical phenotype due to having a normal...