Searchable abstracts of presentations at key conferences in endocrinology

ea0064007 | Low dose continuous IV etomidate for severe Cushing’s syndrome in the non-critical care setting: a clinical study | BES2019

Low dose continuous IV etomidate for severe Cushing’s syndrome in the non-critical care setting: a clinical study

Constantinescu SM , Lefebvre A , Furnica RM , Maiter D

Introduction: Severe Cushing’s syndrome (CS) is defined by extremely high serum cortisol levels (usually >1000 nM), along with severe and deadly complications, including sepsis, heart failure, acute psychosis, vascular thrombosis, digestive haemorrhage and bowel perforation. Rapid control of such hypercortisolism is mandatory and has been shown to decrease operative mortality and complications. Oral treatments such as ketoconazole and metyrapone are often inadequate i...

ea0097011 | Section | BES2023

Development of the KASAI score as a predictive tool for the uni- or bilateral form of primary hyperaldosteronism

G Pierman , D Maiter , RM Furnica

Adrenal venous sampling (AVS) is considered as the gold standard test for primary aldosteronism (PA) subtype diagnosis. However, it is also an invasive and technically challenging procedure. In order to reduce the use of AVS, we propose a new score predicting a unilateral (UPA) or bilateral (BPA) form of PA using biological and radiological parameters. The score was retrospectively developed on a cohort of 72 patients who underwent AVS at the Cliniques Universitaires St-Luc Br...

ea0029p850 | Endocrine tumours and neoplasia | ICEECE2012

Evaluation of beta-cell function and insulin sensitivity in a large series of insulinomas in one single tertiary centre

Furnica R. , Gigot J. , Deprez P. , Buysschaert M. , Maiter D.

Background: Patients with an insulinoma are at variable risk of severe hypoglycemia due to wide ranges of both tumoral insulin secretion and peripheral tissue sensitivity to chronic hyperinsulinaemia.Objectives: In this study we investigated the clinical, biological and tumoral characteristics of a large series of patients with immunohistochemically confirmed insulinoma and we assessed both insulin sensitivity and beta-cell function in fasting steady-sta...

ea0057035 | Pituitary metastasis from follicular thyroid carcinoma – a case report | BES2018

Pituitary metastasis from follicular thyroid carcinoma – a case report

Orioli L , Fomekong E , Duprez T , Daumerie C , Maiter D

A 64-year-old Algerian woman was transferred to our institution with a pituitary tumor causing severe visual impairment. Magnetic resonance imaging (MRI) showed a T1-isointense, T2-hyperintense sellar mass measuring 48×35×30 mm, with homogenous enhancement after gadolinium injection (Figure 1). This mass extended to the suprasellar region, compressing the optic chiasma, and to both cavernous sinus, completely surrounding and narrowing carotid arteries. Ophthalmologic...

ea0064030 | A sarcoidosis-lymphoma syndrome revealed by hypopituitarism | BES2019

A sarcoidosis-lymphoma syndrome revealed by hypopituitarism

Delcourt C , Yidiz H , Camboni A , Van den Neste E , Thissen J P , Maiter D , Furnica R

Introduction: Sarcoidosis is a systemic disease of unknown aetiology, characterized by non-caseified granulomatous reaction that can involve multiple organs. The disease typically presents with pulmonary infiltrates, bilateral hilar and mediastinal lymphadenopathy and uveitis, but may also less frequently affect other organs, including the hypothalamic-pituitary axis. Malignancy rates in sarcoidosis patients have been reported as 1 to 2%1,2, chronic inflammation bei...

ea0064033 | A rare double cause of primary hyperparathyroidism | BES2019

A rare double cause of primary hyperparathyroidism

Hospel J , Lacroix V , Mourad M , Marbaix E , Camboni A , Furnica RM , Maiter D

Case: A 56-year-old patient was referred to our endocrinology unit for management of severe hypercalcemia. He had complained initially from asthenia, intractable nausea and vomiting and weight loss (10 kg), but now also suffered from polyuria-polydipsia, bradypsychia and bradylalia, and diffuse joint pain with loss of strength in the lower limbs. Initial laboratory investigations showed a parathyroid crisis with marked increases of parathyroid hormone (PTH) at 2138.5 pg/ml (45...

ea0026p246 | Pituitary | ECE2011

AcroBel-2: the Belgian follow-up survey on acromegaly: contribution of pituitary surgery and the use of pegvisomant to an improvement in disease control

Bex M , Abs R , T'Sjoen G , Corvilain B , Velkeniers B , Maiter D

Two nationwide surveys on acromegaly (AcroBel-1 and 2) have been performed in Belgium at an interval of five years, including centralized GH and IGF1 measurements in most patients. A normal IGF1 for age was observed in 56% of 311 vs 74% of 365 treated patients, in 2004 and 2009 respectively.Factors responsible for this improvement were investigated. A selection bias was unlikely as the follow-up rate was higher in patients with active (83%) or medically ...

ea0011p510 | Endocrine tumours and neoplasia | ECE2006

AcroBel: a registry and survey on acromegaly in Belgium

Bex M , Abs R , T’Sjoen G , Mockel J , Velkeniers B , Maiter D

To evaluate the epidemiology and global quality of care of acromegaly in Belgium, all endocrinologists treating patients with acromegaly were invited to participate in a nationwide survey extending from 15-6-2003 till 30-9-2004, aiming to include all patients (including deaths) that were in follow up or newly diagnosed after 1-1-2000. The project was ethically approved and written informed consent obtained. Retrospective data on demographics, pathology, complications and treat...

ea0088016 | Abstracts | BES2022

Mortality-related risk factors of inpatients with diabetes and COVID-19: a Multicentric Retrospective Study in Belgium

T Servais , F Laurent , C Litvine , Groote E De , V Godart , E Repetto , M Ponchon , P Chasseur , L Crenier , Eeckhoudt S Van , J Yango , P Oriot , M Gavriliu , S Rouhard , B Deketelaer , C Bugli , L Belkhir , D Maiter , M.P Hermans , JC Yombi , Laura Orioli

Purpose: We describe the characteristics and prognosis of inpatients with diabetes and coronavirus disease 2019 (COVID-19) in Belgium.Methods: We conducted a multicentre retrospective study during the first wave of the pandemic, from March 1, 2020 to May 6, 2020. Data on admission of patients with diabetes and hospitalized due to confirmed COVID-19 were collected. COVID-19 diagnosis was based on a positive polymerase chain reaction (PCR) test on nasophar...