ea0083rdp3 | Reproductive and Developmental Endocrinology | EYES2022
F. Costantino
, G. Spaggiari
, L. Dalla valentina
, C de Angelis
, E Ferrante
, C. Furini
, F Garifalos
, R. Indirli
, F Lombardo
, G. Mantovani
, D Menafra
, M Notarianni
, F Pallotti
, R Pivonello
, M. Romeo
, M. Simoni
, D. Santi
State of the art: In pharmacology, human chorionic gonadotropin (hCG) is considered equivalent to luteinising hormone (LH) since both act on the same receptor. Thus, when testicular function needs to be clinically restored (i.e. in case of hypogonadotropic hypogonadism [HH]), hCG is used instead of LH. However, growing evidences showed LH and hCG activate different molecular pathways and offer different outcomes in women undergoing assisted reproduction. The different action b...