ea0098b3 | Basic Science | NANETS2023
Nunez Jose E.
, Bruce Jeffrey
, Danesh Arnavaz
, Chan David L.
, Rodriguez-Freixinos Victor
, Hallet Julie
, Myrehaug Sten
, Law Calvin
, Pugh Trevor
, Singh Simron
Background: The treatment of neuroendocrine neoplasms (NENs) of higher grade remains a dilemma. In these patients the role of immunotherapy is still unclear and predictive biomarkers are an unmet need. Herein, we present a revised translational analysis of the NET001 and NET002 (NCT03278405, NCT03278379) clinical trials.Methods: Patients with advanced WHO G2-3 NENs who had a gastroenteropancreatic (GEP) or a bronchial primary (excluding typical carcinoid...