Searchable abstracts of presentations at key conferences in endocrinology

ea0086p144 | Thyroid | SFEBES2022

Human chorionic gonadotropin (hCG) mediated thyrotoxicosis secondary to metastatic choriocarcinoma

Page Tristan , Dar Shujah

This female patient presented acutely with headache and neck pain associated with vomiting. Neurological examination was normal. Urine pregnancy test prior to imaging was unexpectedly positive. CT head demonstrated a 2.5x1.5 cm hyperattenuating lesion at the left frontoparietal region. Thyroid function tests were in keeping with thyrotoxicosis (TSH <0.01 mU/l, free T4 37.2 pmo/l, free T3 >30.7 pmo/l). Antithyroid medication was commenced and TSH receptor antibody reque...

ea0074ncc36 | Highlighted Cases | SFENCC2021

Asymptomatic primary hyperparathyroidism-acute deterioration with intercurrent illness-hypercalcaemic crisis

Akhter Rabia , Dar Shujah

Case history: 80 year old male was referred to endocrine clinic for incidental hypercalcemia picked up on six monthly blood tests for follow up of treated carcinoma of prostate in remission. Patient himself complained only of mild mechanical backache and no other symptoms of hypercalcemia. There was no family history of thyroid or parathyroid related disorders. Drug history did not include thiazides or lithium. Investigations: serum calcium 2.75 mmol/l, ...

ea0074ncc71 | Highlighted Cases | SFENCC2021

Polycystic ovarian syndrome-atypical presentation with severe hyperandrogenism

Akhter Rabia , Dar Shujah

Case History: 27 year old female was referred to endocrine clinic with complaints of excess hirsutism over face, chin and neck accompanied with oligomenorrhea and acne for three years. The hirsutism was worsening gradually and she had to shave or wax her facial hair on daily basis. She was born at full term and had menarche at 12 to 13 years of age with regular periods. She had no symptoms of galactorrhea, headache, visual problems or recent weight gain. There was no family hi...

ea0065p53 | Adrenal and Cardiovascular | SFEBES2019

Adrenal suppression following Herbal remedy for Nasal Polyps....not to be sniffed at

Kauser Samina , Shepherd Lisa , Dar Shujah , Lawson Alex , Shakher Jayadave

A 69-year-old South Asian male presented in A+E with hyponatremia. He had pervious history of Lyme Node TB (treated 2014), Asthma and Nasal Polyps. Medication history, patient was taking Fludrocortisone nasal spray for the 30–40 years and Seretide inhaler. Also, CT scans at admission did not identify relapse in Lyme Node TB. Upon investigation he was found to have undetectable morning cortisol (<28 mmols). He was started on Hydrocortisone 10 mg, 5 mg and 5 mg regime, ...

ea0028p14 | Bone | SFEBES2012

Unusual presentation of idiopathic hypoparathyrodism with hyper-CK-emia

Dar Shujah , Bapat Anjaneya , Jahagirdar Vidya , Geevarghese Cheriyan

We report a case of a 51 year-old gentleman with increased serum creatine kinase (CK) due to hypocalcaemic tetany caused by idiopathic hypoparathyrodism. Raised CK (1738 u/L) was incidentally noted in this patient by his GP. He had ongoing symptoms of hypocalcaemia with intermittent tetanic spasms in his hands and scalp and easy fatigability for 2 years. His examination showed normal stature, no evidence of myopathy with normal deep tendon reflexes, Trousseau’s sign was p...

ea0063p7 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

A rare association of Adrenocortical carcinoma with haematological and breast malignancy in a young female

Shafqat Muhammad Murtaza , Khalily Naveed , Deol Herpret , Naeem Aamir , Dar Shujah

A 20-year-old female admitted under haematology team for acute myeloid leukaemia. During her admission, she had a whole body CT scan and was found to have a left breast lesion (proven on biopsy to have invasive ductal carcinoma) and a right adrenal mass measuring 6.5 × 7.5 cm with radiological features suggestive of an adrenocortical cancer. Biochemical workup showed raised adrenal androgens: DHA Sulphate 14.9 umol/l (4.0–11.0), 17-OH Progesterone 7.6 nmol/l (0.6&#15...

ea0059p041 | Bone and calcium | SFEBES2018

Management of osteogenesis imperfecta in adulthood – a single centre experience

Dar Shujah , Khalily Naveed , Khan Shakib , Kamwa Vicky , Cole Trevor , Ayuk John , Gittoes Neil , Hassan-Smith Zaki

Introduction: Osteogenesis imperfecta (OI) is a genetic, heterogeneous, connective tissue disorder most commonly caused by mutations in type I collagen genes. A hallmark of disease is frequent fractures that are precipitated by minimal trauma. There are limited data on the impact of OI on non-skeletal outcomes across the lifecourse. We present cross-sectional data of one of the largest single centre patient cohorts of OI in adulthood (n=186).The aim of this study was ...