Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep331 | Clinical case reports - Thyroid/Others | ECE2016

Overdiagnosis of osteoporosis in a patient with short stature and partial growth hormone insensitivity due to misinterpretation of dual-energy X-ray absorptiometry (DEXA)

Floroskoufi Paraskevi , Daraki Vasiliki , Stratakis John , Kalikakis George , Papavasiliou Stathis

Introduction: Bone densitometry is currently one of the mainstays in the evaluation of systemic bone diseases. The most frequently assessed densitometric parameter is areal bone mineral density (BMD), measured by dual energy X-ray absorptiometry (DEXA) and expressed as g/cm2. However BMD is a bone size-dependent measure and may be found inappropriately low in children and adults with short stature. Osteopenia/osteoporosis have been described in patients with short s...

ea0022p415 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Atypical bronchopulmonary carcinoid tumor metastatic to endocrine glands and bone marrow

Daraki Vasiliki , Stamou Konstantina , Mamalaki Evangelia , Kalikakis George , Papavasiliou Stathis

Bronchopulmonary neuroendocrine tumors (BP-NETs) comprise 20% of all lung cancers. Typical low grade carcinoid tumors (TC) represent the majority of BP-carcinoids. Intermediate grade atypical carcinoid tumors (AC) are less often encountered but more aggressive. Although metastatic dissemination to mediastinal lymph nodes as well as liver, skeleton, central nervous system, skin and mammary glands is well known, the involvement of endocrine glands is really rare.<p class="ab...

ea0049gp32 | Adrenal 3 | ECE2017

Multiple pathologic fractures as the presenting manifestation of Cushing’s syndrome in patients with vitamin D receptor FokI gene polymorphism

Daraki Vasiliki , Floroskoufi Paraskevi , Liarigkovinos Theodoros , Chrysoulaki Maria , Tsamadias Vasilios , Economou Emmanuel , Papavasiliou Stathis

Rare cases of Cushing’s syndrome have been diagnosed only based upon bone manifestations. Fracture risk is related to individual susceptibility to glucocorticoids that is genetically determined by several factors, including VDR gene polymorphism.We report three patients with VDR FokI gene polymorphism and multiple non-traumatic pathologic fractures as the presenting manifestation of Cushing’s syndrome.The second case is a...

ea0049ep1418 | Thyroid (non-cancer) | ECE2017

Development of papillary thyroid carcinoma in a patient with multiple solid cell nests of the thyroid

Liarigkovinos Theodoros , Daraki Vasiliki , Floroskoufi Paraskevi , Moustou Helen , Kalikakis George , Papavasiliou Stathis

Introduction: Solid cell nests (SCNs) of the thyroid are considered embryological remnants of the ultimobranchial bodies and the thyroid diverticulum. They are frequently (61–89%) detected in the thyroid gland, but their biological significance remains disputable. According to the fetal cell thyroid carcinogenesis hypothesis SCNs may act as a source for specific thyroid cancer stem cells generating distinct thyroid cancer phenotypes. We report a case of a patient with con...

ea0037ep1186 | Clinical Cases–Pituitary/Adrenal | ECE2015

Spontaneous pneumocephalus associated with a giant craniopharyngioma

Daraki Vasiliki , Papadaki Efrosini , Zampoulakis Nikos , Mamalaki Evangelia , Kalikakis George , Papavasiliou Stathis

Introduction: Pneumocephalus is defined as the presence of air within the cranial cavity. It is usually associated with neurosurgical procedures but can also be caused by craniofacial trauma, infections and tumours of the skull base and rarely can occur spontaneously. Neoplasms involving the pituitary fossa are unusual causes of spontaneous pneumocephalus.Case report: A 39-year-old man presented in the emergency department with significant visual loss, h...

ea0032p697 | Neuroendocrinology | ECE2013

Impact of long acting somatostatin analogs vs successful surgery on glucose metabolism in Cretan acromegalic patients

Daraki Vasiliki , Konstantinidou Chrystalla , Karipidou Evgenia , Spyrou Fotis , Volanaki Eleni , Mamalaki Evangelia , Papavasiliou Stathis

Introduction: Acromegaly is associated with increased cardiovascular morbidity and mortality, in part, as a consequence of the increased insulin resistance that frequently accompanies GH hypersecretion. Glucose tolerance may worsen in patients treated with somatostatin analogs (SSA).Objective: To compare the long term effects of SSA treatment to successful surgery on glucose metabolism in Cretan acromegalic patients.Design and meth...

ea0056p13 | Adrenal cortex (to include Cushing's) | ECE2018

Hypoglycemic coma as first manifestation of primary adrenal insufficiency in a septic patient with severe hypokalemia and hypomagnesemia

Chrysoulaki Maria , Daraki Vasiliki , Betsi Grigoria , Sfakiotaki Maria , Dolapsaki Maria , Liarigkovinos Theodoros , Stylianou Kostas , Samonis George

Introduction: Adrenal crisis due to primary adrenal insufficiency may result in severe morbidity and mortality if undiagnosed or ineffectively treated. Main manifestations are hypotension (>90%), hyponatremia (70–80%), and hyperkalemia (30–40%), while hypoglycemia is rare. An unusual case of a septic patient with hypokalemia and hypomagnesemia with hypoglycemic coma as first manifestation of acute adrenal insufficiency is presented.Case pre...

ea0037gp.14.04 | Diabetes and obesity – Clinical diabetes | ECE2015

Parental obesity in association with offspring cognitive and psychomotor development at 4 years of age: the mother child ‘Rhea' cohort in Crete, Greece

Daraki Vasiliki , Georgiou Vaggelis , Koutra Katerina , Kyriklaki Andriani , Kampouri Mariza , Sarri Katerina , Vassilaki Maria , Papavasiliou Stathis , Kogevinas Manolis , Chatzi Leda

Introduction: Animal studies suggest that maternal obesity may impact foetal brain structure and function and increase long-term susceptibility to neurodevelopmental and neuropsychiatric disorders. Few human studies have examined these associations with conflicting results. It is unclear if reported associations are due to genetic background or intrauterine mechanisms.Objective: To investigate the association of maternal and paternal obesity status with ...

ea0014p587 | (1) | ECE2007

Secondary hypothalamic amenorrhea as the initial manifestation of HIV infection

Tzifa Garyfallia , Kalikakis George , Zaganas Ioannis , Spiliotis Martha , Kofteridis Diamantis , Daraki Vasiliki , Petkova Valentina , Tzoutzouraki Paraskevi , Papavasileiou Stathis

Hypothalamic hormonal deficiency and anterior pituitary hormonal deficiency is a rare occurrence in patients presenting with HIV infection. We describe a patient with HIV infection who presented with secondary amenorrhea as the initial manifestation.Case report: A 34-year-old woman with previously regular menses presented with secondary amenorrhea by 9 months. The patient had mild gait instability for 7 months; anorexia and weight loss (10 kg) for the la...

ea0073pep10.2 | Presented ePosters 10: Thyroid | ECE2021

Graves’ disease and concurrent immune thrombocytopenia in a patient with albinism following alemtuzumab treatment for multiple sclerosis: a rare case report

Daraki Vasiliki , Eleni-Konstantina Syntzanaki , Mastorodemos Vasileios , Kontolaimaki Kalliopi , Mytilinaiou Maria , Chrysoulaki Maria , Sfakiotaki Maria , Betsi Grigoria , Xekouki Paraskevi

IntroductionAlemtuzumab is an anti-CD52 antibody, leading to lysis and transient depletion of T and B lymphocytes. Its therapeutic effect is mediated by the alteration in immune repertoire that accompanies subsequent lymphocyte reconstitution. It is mainly used for the treatment of relapsing–remitting multiple sclerosis (RRMS). Common side effects are autoimmune diseases, including thyroid disease (>40%), immune thrombocytopenia (IT...