Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep925 | Thyroid (non-cancer) | ECE2015

A case of primary hypothyroidism initially presenting with massive pericardial effusion

Apaydin Mahmut , Beysel Selvihan , Demirci Taner , Cakal Erman , Delibasi Tuncay

Introduction: Although pericardial effusion is a common finding in primary hypothyroidism, massive pericardial effusion or pericardial tamponade are rare. Herein, we describe a newly diagnosed case of primary hypothyroidism initially presenting with massive pericardial effusion.Case report: A 64 years old male patient attended to the emergency unit with worsening dyspnea over the past 1 month. ECG showed a low voltage QRS wave. Chest X-ray showed increas...

ea0041ep76 | Adrenal cortex (to include Cushing's) | ECE2016

A rare case of ectopic ACTH syndrome originated from malignant renal paraganglioma

Tutal Esra , Yilmazer Demet , Demirci Taner , Cakal Erman , Cakir Evrim , Celep Bahadir , Topaloglu Oya , Delibasi Tuncay

Introduction: Ectopic adrenocorticotropic hormone (ACTH) syndrome is characterized by hypercortisolism due to the hypersecretion of non-pituitary ACTH-secreting tumor leads to the Cushing’s syndrome. Herein, we present a case with Cushing’s syndrome, which is diagnosed ACTH-secreting renal malignant paraganglioma.Case: A 40-year-old woman presented with a 5 month history of newly diagnosed hypertension and diabetes, weakness, hyperpigmentation,...

ea0041ep447 | Diabetes (to include epidemiology, pathophysiology) | ECE2016

The association between the FTO gene and gestational diabetes mellitus

Beysel Selvihan , Alp Yunus , Alparslan Pinarli Ferda , Cakal Erman , Yesilyurt Ahmet , Delibasi Tuncay

Introduction: Common polymorphisms of the fat mass and obesity associated gene (FTO) is known to associate with increased obesity and diabetes mellitus type 2. This was the first study to investigate the association between the rs9939609 FTO gene polymorphism and gestational diabetes mellitus (GDM) in Turkish women.Patients and methods: The case-control study included 203 gestational diabetes and 191 non-diabetic pregnant controls. Anthropometric and bio...

ea0032p143 | Calcium and Vitamin D metabolism | ECE2013

Cystic parathyroid adenomas: ultrasonography features

Karbek Basak , Karakose Melia , Caliskan Mustafa , Bozkurt Nujen Colak , Aslan Muyesser Sayki , Delibasi Tuncay

Introduction: Parathyroid adenomas appear typically as homogeneous, hypoechoic lesions compared to the thyroid on the ultrasonography examination. They can be detected easily when they are more than 1 cm. However, cystic parathyroid adenomas are rare. When present, they appear as decreased echogenic areas in the gland. Extrathyroidal feeding from an artery at one pole of the gland is characteristic which is seen on Doppler imaging. We aimed to present a case series including s...

ea0026p201 | Pituitary | ECE2011

Evaluation of aortic stiffness in the acromegaly patients with remission

Karatay Eylem , Cakal Erman , Gonulalan Gulsum , Dogan Mehmet , Bozkurt Nujen Colak , Ozbek Mustafa , Delibasi Tuncay

Objective: Cardiovascular diseases (CVD) are the most important cause of mortality in acromegaly patients. Noninvasive assessment of aortic stiffness which can be used as an predictor of atherosclerosis, may be of benefit in acromegaly patients for early diagnosis of CVD. We evaluated the aortic elasticity parameters of acromegalic patients in remission and compared with healthy controls.Methods and results: Study subjects consisted of 20 patients with a...

ea0022p139 | Cardiovascular endocrinology and lipid metabolism | ECE2010

Echocardiographic epicardial fat thickness in acromegaly patients

Gonulalan Gulsum , Ozbek Mustafa , Cakir Evrim , Colak Nujen , Cakal Erman , Delibasi Tuncay

Objective: Acromegaly is associated with increased morbidity and mortality, mostly due to cardiovascular complications. The objective of the present study was to evaluate the echocardiographic epicardial fat thickness in acromegaly patients.Methods and results: We evaluated 25 consecutive patients with acromegaly (15 females, 10 males, mean age 44.5±10.1 years), and 22 age-matched control subjects (12 females, 10 males, mean age 37.40±7.5 years...

ea0022p270 | Diabetes | ECE2010

A case of diabetic ketoacidosis with ECG abnormalities mimicking acute coronary syndrome

Ozkaya Evrim Cakir , Ozbek Mustafa , Bozkurt Nujen Colak , Cakal Erman , Karbek Basak , Delibasi Tuncay

Diabetic ketoacidosis (DKA) seen in 10–70% of patients with type 1 diabetes mellitus (DM1) has a significant risk of mortality. We present a DKA in a patient with DM1 resulted in hypokalemia related ECG abnormalities that the diagnosis needed to be differentiated from acute coronary syndrome. A 18-year-old women without any significant past medical history admitted to hospital with a two day history of fatique, weakness, nausea, vomiting. Patient appeared hipovolemic. Vit...

ea0022p370 | Endocrine Disruptors | ECE2010

Association between ischemia-modified albumin and oxidative stress markers in patients with metabolic syndrome

Ozbek Mustafa , Cakir Evrim , Colak Nujen , Cakal Erman , Aliyazicioglu Yuksel , Mentese Ahmet , Turan Ibrahim , Delibasi Tuncay

Objective: The aim of this study was to determine the change in serum ischemia-modified albumin (IMA) level and oxidative stress markers (total antioxidant status, TAS, total oxidant status, TOS) in patients with metabolic syndrome (metS).Research design and methods: We studied 52 metS patients (56.74±12.75 mean age), and 36 control subjects (54.47±6.52 mean age). The presence of metS was diagnosed according to National Cholesterol Education Pr...

ea0020p84 | Thyroid | ECE2009

Clinicopathologic features of incidental and nonincidental papillary thyroid microcarcinoma

Ozuguz Ufuk , Berker Dilek , Aydin Yusuf , Isik Serhat , Tutuncu Yasemin , Delibasi Tuncay , Guler Serdar

Objective: Most of the papillary thyroid microcarcinomas (PTMC) are incidentally discovered in pathological examination after the surgery of benign thyroid disorders. The purpose of the present study was to evaluate clinicopathologic features of incidental and nonincidental PTMC.Material and methods: We evaluated 56 patients with PTMC between 2003 and 2008 at the Division of Endocrinology of the Numune Training and Research Hospital. We analyzed the tumo...

ea0020p148 | Thyroid | ECE2009

Incidental thyroid carcinoma in patients with thyrotoxicosis

Isik Serhat , Berker Dilek , Aydin Yusuf , Ozuguz Ufuk , Akcil Gulhan , Delibasi Tuncay , Guler Serdar

Objective: Thyroid malignancy detected incidentally in patients who underwent surgery for thyrotoxicosis has been reported at different rates. The aim of this study was to investigate the rate of incidental thyroid carcinoma (ITC) in thyrotoxic patients underwent surgery in our institution.Methods: The prevalence of ITC was investigated in patients who underwent surgery for Graves’ disease (GD), toxic adenoma (TA) or toxic multinodular goiter (TMNG)...