Searchable abstracts of presentations at key conferences in endocrinology

ea0016p662 | Signal transduction | ECE2008

Corticotropin releasing hormone receptor signalling pathways and regulation of NOSIII activity in syncytialized BeWo cells

Delidaki Maria , Gu Mei , Vatish Manu , Grammatopoulos Dimitris

Placental corticotrophin releasing hormone (CRH) appears to play important physiological roles during pregnancy and labour. In the placenta, CRH appears to regulate diverse actions such as human trophoblast cell grown and invasion, tissue remodeling, direct modulation of the placental prostaglandin generation and bioavailability and control of placental vascular tone through regulation of endothelial NOS (NOSIII) expression and activation1. CRH actions are mediated ...