Endocrine Abstracts

Thyroid ultrasound (US) is a useful tool in a spectrum of thyroid conditions. In some hospitals, primary care has direct access to requesting thyroid US, rather than via a speciality. We were keen to assess the outcomes of thyroid US referred by primary care.We analysed all primary care referrals for thyroid US, retrospectively, during the first six months of 2006 and analysed them according to the following 3 reasons for referral – 1) suspicion of ...

HTLV-1 associated lymphoma is a rare but well recognised cause of life-threatening hypercalcaemia. It carries a very poor prognosis. We describe a case of a 47 year old Afro-Caribbean lady who presented with 3 months of fever, weight loss and right hip pain. She had a past medical history of quiescent sarcoidosis diagnosed 20 years previously. She also suffered from systemic lupus erythematosus, for which she was taking methotrexate and 20 mg of prednisolone. She also had hype...

The prevalence of thyroid nodules is extraordinarily common. An increase in the use of head and neck imaging, including ultrasound, computed tomography (CT) and carotid Dopplers, has increased the number of non-palpable thyroid nodules identified. For most patients, their thyroid disease is non-neoplastic and asymptomatic. The challenge in the management of thyroid nodules is identifying patients with clinically significant disease, most notably thyroid neoplasia, without exce...

Multiple Endocrine Neoplasia is characterised by the occurrence of tumours involving two or more endocrine glands within a single patient. MEN are autosomal dominant disorders. Four forms have been described: MEN 1 due to menin mutations, MEN2 (previously MEN2A) due to mutations of a tyrosine kinase receptor encoded by the rearranged during transfection (RET) protoncogene, MEN3 (previously MEN2B) due to RET mutations and MEN4 due to cyc...

Multiple Endocrine Neoplasia is characterised by the occurrence of tumours involving two or more endocrine glands within a single patient. MEN are autosomal dominant disorders. Four forms have been described: MEN 1 due to menin mutations, MEN2 (previously MEN2A) due to mutations of a tyrosine kinase receptor encoded by the rearranged during transfection (RET) protoncogene, MEN3 (previously MEN2B) due to RET mutations and MEN4 due to cyc...