Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep957 | Steroid metabolism + action | ECE2016

Similarity and differences of maximal and sub-maximal endurance exercise in increase the serum testosterone and DHT concentrations in healthy males

Sgro Paolo , Sansone Massimiliano , Romanelli Francesco , Lenzi Andrea , Bianchini Serena , Luigi Luigi Di

Introduction: Physical exercise exerts several effects on endocrinological homeostasis and, in particular, sprint exercise elicits the largest testosterone response per unit of work, while in response to prolonged endurance exercise testosterone levels will typically decline. In contrast to a large amount of paper about the modification of testosterone during physical exercise few study evaluated how DHT was influenced by a single bout of aerobic exercise.<p class="abstext...

ea0016p11 | Adrenal | ECE2008

Phosphodiesterase inhibitors and adrenal response to exercise-related stress

Sgro Paolo , Gallotta Maria Chiara , Emerenziani Gian Pietro , Fierro Valentina , Guidetti Laura , Baldari Carlo , Romanelli Francesco , Lenzi Andrea , Di Luigi Luigi

Worldwide numerous active individuals take phosphodiesterase type 5 inhibitors (PDE-5i), furthermore, to our knowledge, the effects of these drugs on hormone secretion has not been adequately investigated. In particular, considering that a) PDE-5i influence NO bioavailability, b) NO is one of the mediators of the hypothalamus┬ľpituitary┬ľadrenal (HPA) axis response to stress, and, c) physical exercise-related stress activate HPA axis, we investigated whether PDE-5i inf...