Endocrine Abstracts

Introduction: Autosomal dominant hypocalcemia (ADH) type 1 is a rare form of hypoparathyroidism, caused by heterozygous, inherited or de novo, activating mutations in the CASR. CASR is also expressed in the kidney and activating mutations lead to decreased calcium renal absorption. Activating mutations in the CasR, inhibits salt transport, leading to Bartteŕs syndrome (BS) type V which can co-exist with ADH1. Chronic myeloid leukemia (Cml) is characterized by the...

Introduction: Immune checkpoint inhibitors (ICIs), are widely used as therapeutic option in oncological patients. However, ICIs treatment is often complicated by endocrinological adverse events, such as hypophysitis. Although diagnostical approach of hypophysitis is standardized, imaging features have not been characterized yet. Methods: Pituitary gland magnetic resonance imaging (MRI) findings were retrospectively recorded in 59 oncological patients wit...