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Endocrine Abstracts

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ea0026p48 | Endocrine disruptors | ECE2011

The role of progestins in the interplay of estradiol and genistein: influences on the steroid hormone receptor expression patterns in distinct uterine compartments

Moller F , Honschied P , Zierau O , Diel P , Vollmer G

Ovariectomized (OVX) rats are commonly used for the investigation of estrogenic compounds in vivo. We previously showed that estrogen treated OVX animals apparently respond differently to Genistein (GEN) treatment than hormonally intact animals. An observation, that indicated that progestins might interfere in the estradiol (E2)–GEN interaction.As the molecular effects of GEN seem to be modified by progesterone (P4), its...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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