Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep589 | Diabetes therapy | ECE2017

Dapagliflozin induced vulvovaginitis in an atopic patient with type 2 diabetes mellitus

Nasiroglu Imga Narin , Catak Merve , Berker Dilek

Introduction: Dapagliflozin is sodium-glucose co-transporter receptor 2 (SGLT2) inhibitor that is recently discovered an oral antidiabetic (OAD) agent that improves glycemic control by increasing the renal excretion of glucose. Vulvovaginal candidiasis (VVC) is the infection of the vaginal vestibuler area. We present a case of VVC accompanied by use of dapagliflozin.Case: A-48-year-old woman who had T2DM since 8 years was admitted to the endocrinology cl...

ea0056p1066 | Thyroid (non-cancer) | ECE2018

The effects of exenatide treatment on thyroid

Koseoglu Derya , Baser Ozden Ozdemir , Berker Dilek

Glucagon-like peptide-1 (GLP-1) is an increatin hormon with various glucoregulatory effects, and exenatide is a GLP-1 receptor agonist used in the management of type 2 diabetes mellitus. C cell hypertrophy was seen in animals treated with GLP-1 receptor agonists, but the effects of GLP-1 agonists on C-cell proliferation or neoplasia in humans have not been documented formerly. The aim of this study was to evaluate the impact of exenatide on structural and functional features o...

ea0049ep287 | Calcium & Vitamin D metabolism | ECE2017

PTH levels in vitamin D deficiency

Catak Merve , Koseoglu Derya , Baser Ozden Ozdemir , Berker Dilek

Introduction: High level of Parathormone (PTH) impair bone health by increasing the risk of fracture. The aim is to determine the threshold value of PTH elevation to accompany deficiency or failure of Vit D. This may be an important parameter in assessing bone metabolism in clinical practice.Material and method: 931 patients who were referred to the endocrinology clinic were retrospectively studied and 880 patients diagnosed with Vit D deficiency include...

ea0049ep1425 | Thyroid (non-cancer) | ECE2017

Is Hashimoto’s thyroiditis a risk factor for papillary thyroid cancer?

Cetin Zeynep , Baser Ozden Ozdemir , Berker Dilek , Guler Serdar

Aim: Hashimoto’s thyroiditis (HT) is the commonest autoimmune thyroid disease. Papillary thyroid cancer (PTC) is the most often thyroid cancer and its incidence is increasing yearly. It is not clear that HT is a predisposing factor for PTC. We studied PTC’s frequency among HT patients went to total thyroidectomy.Materials and methods: Five hundred and thirty four patients done total thyroidectomy by general surgery were evaluated retrospectivel...

ea0041ep1050 | Thyroid (non-cancer) | ECE2016

Relation between Serum 25-hydroxy-vitamin D Levels and TSH receptor antibody seropositivity

Saglam Fatma , Koseoglu Derya , Berker Dilek , Guler Serdar

Objective: Vitamin D is an immune-modulator that may play a role in thyroid related autoimmunity. But the relation between Vitamin D and Graves’ disease (GD) is not well defined yet. The aim of this study was to investigate the association of 25-hydroxy-vitamin D (25[OH]D) levels and TSH receptor antibody (TRab) levels in GD.Design: A total of 429 GD patients were analyzed retrospectively. 122 of 429 patients had vitamin D levels were enrolled in th...

ea0022p815 | Thyroid | ECE2010

Evaluation of theurapeutic modalities in Graves' hyperthyroidism

Yalcin Yavuz , Topaloglu Oya , Berker Dilek , Isik Serhat , Guler Serdar

Objective: Currently there are three well-established treatment options for hyperthyroid Graves’ disease (GD): antithyroid drug therapy with thionamides, radioactive iodine (RAI) treatment with (131)I, and surgery. The aim of this study was to investigate retrospectively theurapeutic options of the patients with GD treated at outpatient clinics of Endocrinology and Metabolism between January 2007 and December 2009.Methods: We evaluated 122 patients ...

ea0056p876 | Pituitary - Clinical | ECE2018

The change in metabolic parametres of prolactinoma patients after therapy intervention

Dagdelen Duran Iffet , Ersoz Gulcelik Nese , Berker Dilek

Introduction: Prolactinoma is the prolactin secreting tumor of the pituitary gland which exerts mainly hypogonadal complaints and sometimes symptoms due to mass effect. Meanwhile it was mentioned to cause metabolic abnormalities such as increased fasting plasma glucose (FPG), Low Density Lipoprotein(LDL) cholesterol and triglycerides(TG). We studied whether some of these metabolic parametres of prolactinoma patients could be changed after the therapy.Met...

ea0063p345 | Thyroid 1 | ECE2019

Should narrower TSH and free thyroid hormone levels be targeted to reduce the cardiovascular risk of euthyroid subjects?

Cetin Zeynep , Kosem Arzu , Catak Merve , Can Bulent , Baser Ozden , Turhan Turan , Berker Dilek , Guler Serdar

Aim: Thyroid hormones have many effects on the cardiovascular system. May studies have showed that apparent or subclinical hypothyroidism increase the risk of hypertension hyperlipidemia and so lead to atherosclerosis susceptibility. This risk can be reduced by treatment. But, studies on the relationship between thyroid function tests and cardiovascular risk in euthyroid subjects are contradictory. This study was designed to investigate the effect of TSH, free T3, f...

ea0049ep810 | Obesity | ECE2017

Differences in calcium and thyroid homeostasis and thyroid volume after bariatric surgery

Dagdelen Duran İffet , Ersoz Gulcelik Nese , Berker Dilek , Guler Serdar

Introduction: Bariatric surgery would end up with great alterations in homeostatic measures such as glucose and lipid metabolism and hormonal regulation, which of all are interweaved with some number of ways to each other. The hormonal modulation extands along a wide span starting from the change in gastrointestinal peptides, to the effect in insulin and other nutrient metabolism regulatory hormones and even the hormones establishing thyroid and calcium homeostasis. Secondary ...

ea0049ep977 | Pituitary - Clinical | ECE2017

Is there a gender difference in clinically nonfunctional pituitary adenomas?

Duran Iffet Dağdelen , Gulcelik Neşe Ersoz , Berker Dilek , Guler Serdar

Introduction: Clinically nonfunctioning pituitary adenomas (NFPA) are the most common pituitary tumor type. They are usually recognized after they cause symptoms especially when tumor size increases and eventually invades adjacent structures. Nevertheless the discovery would also be accidental. In the literature some kind of gender difference is reported in NFA’s behavioral results such as pituitary axis deficits or consequences of surgery however they resulted with contr...