Endocrine Abstracts

Background: Childhood obesity now represents a major public health concern. Being obese in childhood appears to increase the risk of severe obesity in adulthood. Obesity is associated with co-morbid conditions such as type 2 diabetes and cardiovascular disease. Underpinning obesity is a state of chronic sterile inflammation. Recently the invariant natural killer T (iNKT) cell, an innate T cell was shown to act as a metabolic regulator and altered by obesity both in adults and ...