Searchable abstracts of presentations at key conferences in endocrinology

ea0020p594 | Neuroendocrinology, Pituitary and Behaviour | ECE2009

Dose interval comparison of Lanreotide Autogel 120 mg in acromegalic patients previously treated with Octreotide LAR

Schopohl Jochen , Badenhoop Klaus , Beuschlein Felix , Droste Michael , Plockinger Ursula , Petersenn Stephan , Strasburger Christian

Acromegalic patients under treatment with Octreotide LAR (Oct), 10, 20 or 30 mg were switched to Lanreotide Autogel 120 mg (Lan) at different dose intervals: 56, 42 and 28 days respectively. Just before the fourth Lan injection, IGF-I values were measured and the dose interval for the final three injections adjusted accordingly: if IGF-I values were between 1 and 2 standard deviations (S.D.) above the age and sex related mean value, no change in dose-interval wa...

ea0041ep609 | Endocrine tumours and neoplasia | ECE2016

Craniopharyngioma registry for adult patients, an initiative of the pituitary workgroup of the DGE

Mende Klaus Christian , Kopczak Anna , Deutschbein Timo , Droste Michael , Honegger Jurgen , Stalla Gunther , Muller Herrmann , Petersenn Stephan , Flitsch Jorg

Introduction and Objective: Adult craniopharyngioma as a rare neoplasm of the central nervous system is still very poorly understood. The clinical implications for affected patients are numerous, ranging from endocrine dysfunction to visual loss and neurological impairment. Although the progress of this tumor entity is slow by nature, affected patients often suffer from multiple symptoms even after successful treatment with a strong impact on their individual quality of life. ...

ea0041ep920 | Pituitary - Clinical | ECE2016

Fatigue and subjective complaints in patients with active and controlled acromegaly: a cross sectional multi-center study

Zimmermann Anca , Zwerenz Rudiger , Droste Michael , Schofl Christof , Strasburger Christian J , Plockinger Ursula , Honegger Jurgen , Millaku Bledar , Beutel Manfred E , Weber Matthias M

Introduction: Acromegalic patients (AP) often report fatigue and chronic subjective complaints. We aimed to investigate in more detail these aspects in AP, dependent on disease activity, age, gender, medication and pituitary insufficiency (PI).Patients/methods: Cross sectional, 124 patients (M/W 51/73, age 58.3±14.7 years, 49/75–active/controlled disease). The patients completed the Multidimensional Fatigue Inventory (MFI-20) and the Giessen Su...

ea0035oc5.1 | Adrenal & Thyroid | ECE2014

Diagnostic and therapeutic outcome in ERCUSYN: Preliminary report in over 1000 patients

Valassi Elena , Santos Alicia , Brue Thierry , Netea-Maier Romana T. , Feelders Richard A. , Yaneva Maria , Tsagarakis Stylianos , Pfeifer Marija , Chanson Philippe , Chabre Olivier , Zopf Kathrin , Toke Judit , Wass John AH , Droste Michael , Maiter Dominique , Dusek Tina , Komerdus Irina , Franz Holger , Lamberts Steven W.J. , Strasburger Christian J.

The European Registry on Cushing’s Syndrome (ERCUSYN) is designed to collect prospective and follow-up data on patients with Cushing’s syndrome (CS) and currently (Sep 2013) includes 1006 patients (804 F, 202 M; mean age (+S.D.) 44.7±13.3 years) from 57 centers in 28 countries.Six hundred and sixty one (66%) had pituitary-dependent CS (PIT-CS), 242 (24%) adrenal-dependent CS (ADR-CS), and 103 (10%) CS from other etiologies, ...

ea0056oc12.5 | Novel aspects of puberty development and Cushing's disease | ECE2018

Diabetes mellitus and muscle weakness are independently associated with mortality in patients with Cushing’s syndrome. Data from ERCUSYN

Valassi Elena , Tabarin Antoine , Brue Thierry , Feelders Richard A , Reincke Martin , Neteia-Maier Romana , Toth Miklos , Yaneva Maria , Webb Susan M , Tsagarakis Stylianos , Chanson Philippe , Pfeifer Marija , Droste Michael , Komerdus Irina , Kastelan Darko , Maiter Dominique , Chabre Olivier , Franz Holger , Santos Alicia , Strasburger Christian J , Trainer Peter J , Newell-Price John , Ragnarsson Oskar

Background: Patients with active Cushing’s syndrome (CS) have increased mortality.Aims: Evaluate cause of death in a large cohort of CS patients, and establish factors associated with increased mortality.Methods: We analysed 1514 patients included in the European Registry on Cushing’s syndrome (ERCUSYN): 1022 (68%) had pituitary-dependent CS (PIT-CS), 379 (25%) adrenal-dependent CS (ADR-CS), 71 (5%) had an ectopic source ...