Searchable abstracts of presentations at key conferences in endocrinology

ea0032p439 | Diabetes | ECE2013

Admissions of diabetic patients due to hypoglycemia of external cause in a central hospital from 2006 to 2012

Fonseca Ricardo , Duarte Joao Sequeira

Background: Hypoglycemia is a common complication of Diabetes Mellitus treatment, especially in patients receiving intensive therapy. It can cause severe clinical consequences and is an obstacle to achieve glycemic targets.Methods: Retrospective study of severe hypoglycemia due to insulin or oral drug therapy that lead to hospitalization in a central hospital. We reviewed the medical records in the last 7 years (2006–2012) for blood glucose levels a...

ea0063ep117 | Pituitary and Neuroendocrinology | ECE2019

Primary amenorrhea at age 37 – case report

Roque Catarina , Ferreira Rute , Duarte Joao Sequeira , Oliveira Manuela

A female patient was first referred to the Endocrinology department due to primary amenorrhea at age 37. She mentioned trans-sphenoidal surgery at age 15 due to a craniopharyngioma and the indication to be supplemented with hydrocortisone (HC) and DDAVP, that she adhered to until age 20, when she abandoned all appointments. Apart from that, she mentioned normal pubertal development and said she was generally healthy. She denied any episodes compatible with Addisonian crises. F...

ea0049ep951 | Pituitary - Clinical | ECE2017

Acute presentation of cushing disease: severe hyperglycemia and refractory hypokalemia

Bello Carlos Tavares , Santos Francisco Sousa , Ferrinhos Catia , Serra Filipa Alves , Duarte Joao Sequeira , Vasconcelos Carlos

Introduction: Cushing’s syndrome (CS) is a rare disease resulting from prolonged exposure to supraphysiological levels of glucocorticoids. Cushing’s Disease is the most frequent cause of endogenous CS. This disease has a broad spectrum of clinical manifestations and is associated with an increased morbi-mortality. Diabetes Mellitus (DM) and hypokalemic alkalosis affects up to 50 and 10% of CS patients respectively. Disease onset and severity reflects the magnitude of...

ea0049ep1486 | Thyroid (non-cancer) | ECE2017

Timing to repeat thyroid fine-needle aspiration after a follicular lesion of undetermined significance result - does it matter?

Santos Francisco Sousa , Ferrinho Catia , Capitao Ricardo , Duarte Joao Sequeira , Chorao Martinha , Limbert Clotilde , Vasconcelos Carlos

Introduction: Regarding thyroid nodules, in case of follicular lesion of undetermined significance (FLUS), performing repeat fine-needle aspiration (FNA) is a common follow-up strategy. It has been suggested that a waiting period of at least 3 months between FNAs would increase the diagnostic yield. Our study aims to clarify the optimal time for repeat FNA in case of an initial FLUS result.Methods: We identified retrospectively all thyroid FNA FLUS resul...

ea0041ep344 | Clinical case reports - Thyroid/Others | ECE2016

Type 1 diabetes mellitus and acquired hemophilia

Bello Carlos Tavares , Fonseca Ricardo , Barreiros Catarina , Duarte Joao Sequeira , Esteves Jose , Vasconcelos Carlos

Introduction: Type 1a Diabetes (DM1) is a challenging disease with a rising incidence (up to 40 per 100 000 in Finland and Sardinia) being less common in the African population. It is believed to have an autoimmune basis and has been associated with other autoimmune diseases namely autoimmune thyroiditis and celiac disease. Acquired hemophilia is a rare clinical entity characterized by bleeding diathesis induced by circulating inhibitors to coagulation factors (VIII ou IX) tha...

ea0041ep909 | Pituitary - Clinical | ECE2016

Renal function in acromegaly – experience from a portuguese centre

Bello Carlos Tavares , Fonseca Ricardo , Santos Francisco Sousa , Capitao Ricardo , Duarte Joao Sequeira , Vasconcelos Carlos

Introduction: The Nephron is a known target organ of the Growth Hormone/Insulin-like factor-1 axis. They influence glomerular and tubular function having an important physiological role in water and electrolyte balance, especially in Acromegaly. The aim of the study was to investigate renal function in acromegalic patients during active disease and remission and evaluate hormonal impact on renal function markers.Methods: A retrospective, longitudinal, ob...

ea0041ep966 | Thyroid (non-cancer) | ECE2016

What does matter for AUS/FLUS: size, sex or age?

Rafael Ana Alves , Silva Silvia , Marques Ricardo Rodrigues , Duarte Joao Sequeira , Fernandes Luis Viana

Background: The clinical attitude to the treatment of Bethesda System Category III lesions has been under controversy. Our aim was to analyse three variables and to establish a possible predictive value for carcinoma in patients with AUS/FLUS nodules.Methods: Retrospective study of 671 thyroid fine-needle aspirations (FNAs) classified as AUS/FLUS between January 2012 and June 2015. Size, sex and age were analysed, using SPSS.Result...

ea0037ep539 | Diabetes (complications & therapy) | ECE2015

Type IV renal tubular acidosis in type 2 diabetes: case report of 4 patients

Bello Carlos Tavares , Fonseca Ricardo Castro , Duarte Joao Sequeira , Vasconcelos Carlos

Introduction: Type IV Renal Tubular Acidosis (Type 4 RTA) is an underdiagnosed condition known to be more frequent in Diabetes Mellitus patients with moderate renal impairment. It is thought to be very common, with an incidence of 3.8% of hospital admissions in some series, being an increasing problem among the elderly and aggravated by polypharmacy.Methods/design: The authors describe 4 cases of Type 4 RTA associated with type 2 Diabetes diagnosed and f...

ea0067o38 | Oral Presentations | EYES2019

Non-functioning pituitary adenomas experience of a reference center

Cunha Clara , Ferrinho Catia , Silva Eugenia , Dias Lidia , Marques Conceicao , Chorao Martinha , Saraiva Catarina , Duarte Joao Sequeira

Objective: Describe clinical, laboratorial, imaging features, therapeutic management and the outcomes of patients with clinically non-functioning pituitary adenomas (NFPAs) presenting at our department.Methods: Retrospective review of electronic medical records of all patients with NFPAs evaluated at our department between 2010 and 2019.Results: We evaluated 160 patients, 51.3% female, with a median age of 56.6 years (18–89). ...

ea0067gp20 | Poster Presentations | EYES2019

Pheochromocytoma, unmasking the chameleon

Cunha Clara , Ferrinho Catia , Santos Francisco Sousa , Silva Eugenia , Fernandes Luis Viana , Saraiva Catarina , Oliveira Manuela , Duarte Joao Sequeira

Background: Pheochromocytoma is a rare catecholamine secreting tumor originating usually from adrenal medulla and representing approximately 5% of adrenal incidentalomas. Currently 10% of all pheochromocytomas are discovered incidentally during imaging studies for unrelated disorders.Case presentation: A thirty five year old woman with no relevant medical history presented at the emergency department with symptoms of left flank pain and vomiting. Abdomin...