Searchable abstracts of presentations at key conferences in endocrinology

ea0016p15 | Adrenal | ECE2008

The prevalence of 21-hydroxylase deficiency in adrenal incidentalomas: hormonal and mutation screening

Lazurova Ivica , Wagnerova Hedwiga , Habalova Viera , Dudasova Daniela

The aim of the present study was to evaluate and compare the response of 17 OHP to ACTH stimulation in patients with various types of adrenal incidentalomas and to examine the occurence of germline CYP21 mutation in these patients.Subjects and methods: Forty patients (27 females, 13 males) with unilateral and bilateral masses were screened for five most common mutations of the CYP21 in peripheral blood DNA samples. A hormonal evaluation, i.e. baseline pl...

ea0014p150 | (1) | ECE2007

Adrenal incidentalomas and insulin sensitivity – are there any differences between adenomas and hyperplasia?

Dudasova Daniela , Lazurova Ivica , Wagnerova Hedviga , Dravecka Ingrid

It is well known that adrenal masses, particularly adenomas are frequently related to metabolic syndrome and insulin resistance. However, there are no reported data about the differences between adenomas and hyperplasia.Authors examined the prevalence of symptoms of the metabolic syndrome and insulin resistance in 25 patients with adrenal incidentalomas (10 men, 15 women) of the mean age 57.9+15 years. 15 patients had adrenal adenoma determined by CT or ...