ea0035p931 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014
Navardauskaite Ruta
, Dusatkova Petra
, Obermannova Barbora
, Pfaeffle Roland W
, Blum Werner F
, Adukauskiene Dalia
, Smetanina Natalija
, Cinek Ondrej
, Verkauskiene Rasa
, Lebl Jan
Introduction: Congenital multiple pituitary hormone deficiency (MPHD) may result from defects of transcription factors that govern the early pituitary development. The most prevalent are two mutation of PROP1 gene: the c.296delGA and c.150delA.Methods: Seventy-five Lithuanian MPHD patients were tested for PROP1 defects. Perinatal and postnatal data were obtained from medical records. Hormonal investigations, pituitary imaging and GH the...