Searchable abstracts of presentations at key conferences in endocrinology

ea0025p328 | Thyroid | SFEBES2011

Thyrotoxic crisis: a stormy period on intensive care

Eapen Dilip , D'Costa Ryan

Thyroid storm or thyrotoxic crisis is a manifestation of an extreme state of thyrotoxicosis. It is both rare and potentially fatal. Its presentation can be clouded by the precipitating illness and the involvement of one or more organ systems underlining the importance of clinical suspicion, early recognition and prompt intervention.We present a case of a 37-year-old man presenting to hospital with a community acquired chest infection that had not settled...

ea0065p115 | Bone and calcium | SFEBES2019

Ventricular arrhythmia and cardiac arrest: a dramatic presentation of hypoparathyroidism

James Cornelius Fernandez , Eapen Dilip

Introduction: Cardiovascular manifestations of hypocalcaemia include reversible CHF, prolonged QTc and ventricular arrhythmias. In patients presenting with hypocalcaemia, diagnosis of hypoparathyroidism is straightforward, but determining its cause is challenging.Case Report: 33 year lady admitted (23 November 2018) with VF arrest. Bloods showed low calcium (1.62 mmol/l), magnesium (0.48 mmol/l) and potassium (2.3 mmol/l) and ECG showed prolonged QTc. PT...

ea0065p423 | Thyroid | SFEBES2019

Thyrotoxicosis and post RAI hypothyroidism in someone with thyroid hormone resistance: A conundrum

James Cornelius Fernandez , Eapen Dilip

Introduction: Thyroid Hormone Resistance (THR) is a rare disorder caused by mutations of Thyroid Hormone Receptor characterised by insensitivity of target tissues to thyroid hormone actions. Patients can present with hyperthyroidism or hypothyroidism symptoms.Case report: 49 year lady with recurrent thyrotoxicosis with goitre (1989/1994/1998) treated elsewhere with CBZ/PTU and RAI (2001). She developed post-RAI hypothyroidism and at presentation to our O...

ea0065p427 | Thyroid | SFEBES2019

Managing hypothyroidism without oral levothyroxine

James Cornelius Fernandez , Eapen Dilip

Introduction: Hypothyroid patients with failure to take/absorb oral levothyroxine might require intravenous levothyroxine. IV levothyroxine is neither licensed nor available in UK. It has to be imported (with special request), and is unexpectedly costly. IV liothyronine has shorter duration of action, need 2–3 injections/day, and exhibits sudden surges increasing risk of angina/arrhythmia. Moreover, IV liothyronine is much more expensive than IV levothyroxine.<p class...

ea0025p197 | Endocrine tumours and neoplasia | SFEBES2011

Rare association of simultaneous adrenal Cushing’s and primary hyperparathyroidism in patient with previous Graves disease

Eapen Dilip , D'Costa Ryan , Nagi Dinesh

A 33-year-old lady was referred to the endocrinology clinic with weight gain, hirsuitism and amenorrhea. She had been diagnosed with hypertension a year ago which was difficult to control despite being on three anti-hypertensive agents – Ramipril, Amlodipine and Bendroflumethazide. Past medical history included hypothyroidism secondary to radioactive-iodine therapy for Graves disease aged 22. Her GP organised an ultrasound scan querying polycystic ovaries but this reveale...

ea0025p184 | Endocrine tumours and neoplasia | SFEBES2011

Parathyroid carcinoma: an important differential diagnosis in primary hyperparathyroidism

Kummaraganti Srinivasa , Eapen Dilip , Thomas Jennifer , Prabhakar Karthik

Parathyroid carcinoma is an uncommon cause of PTH-mediated hypercalcaemia, accounting for 0.5–5% of patients with primary hyperparathyroidism. We describe a case of parathyroid carcinoma where the usual pre-operative features of this condition were absent, and hence diagnosed on histopathology.A 72-year-old woman was referred to endocrinology with incidentally noted hypercalcaemia. Past medical history included hypothyroidism and essential hypertens...