Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep451 | General Endocrinology | ECE2021

The (epi)genetic basis of gender incongruence

Fernandez Rosa , Collet Sarah , Ramirez Karla , Kiyar Meltem , Delgado-Zayas Enrique , Guy T’sjoen , Guillamon Antonio , Mueller Sven C , Eduardo Pásaro

In mammals, the gonads and the brain develop from bipotential organs that will differentiate into female or male organs, during a critical period of development. This process begins with the production of testosterone by the testes, which will be converted into estradiol in the brain, by the aromatase. While the end is defined by the moment when the inhibition of androgens (in males), or treatment with estrogens (in females), stops having an effect on brain dimorphism. But in ...