ea0041ep475 | Diabetes (to include epidemiology, pathophysiology) | ECE2016
, Tkacheva Olga
, Boytsov Sergey
, Osipov Georgy
Background: Type 2 diabetes mellitus (T2DM) is a condition of multi-factorial origin, involving several molecular mechanisms related to the intestinal micro-biota for its development. The micro-biota able to favor systemic exposure to the lipopolysaccharides (LPS), large glycolipids derived from the outer membrane of Gram-negative bacteria. LPS can cause a condition of metabolic endotoxemia characterized by low-grade inflammation, insulin resistance.<p class="a...