Endocrine Abstracts

Introduction: The contribution of chronic hepatitis C virus (HCV) infection per se in thyroid autoimmunity and dysfunction remains controversial.Aim: To investigate the prevalence of thyroid disorders and the possible association between thyroid dysfunction and different factors in a cohort of HCV untreated patients.Material and methods: A total 1050 patients with untreated HCV infection were enrolled in this study. Thyroid functio...

A 46-year old male patient, living in Giza, father of 4, used to work as a baker. He is an ex-smoker. He has diabetes on insulin for 4 years, not hypertensive.He was diagnosed to have colonic carcinoma upon which surgical intervention was done in the form of right hemicolectomy with splenectomy and cholecystectomy. Postoperative pathology report revealed invasive moderately differentiated adenocarcinoma. He received postoperative chemotherapy, twelve sessions over the past one...

Background: Dysmetabolic iron overload syndrome (DIOS) is characterized by elevated ferritin and normal transferrin saturation level. Iron metabolism may be linked to the sympathetic overactity. DIOS is seen in 15–20% of the metabolic syndrome cases.Aim: This study aimed to test the hypothesis linking the increased baseline sympathetic drive to the hypertension seen in dysmetablolic iron overload syndrome in cases of metabolic syndrome.<p class=...

Introduction: Thiamine responsive megaloblastic anemia syndrome(TRMA), is an autosomal recessive disorder due to mutation of gene (SLC19A2) encoding thiamine transporter protein TRMA ischaracterized by a triad of anemia, diabetes mellitus, and sensorineural deafness.Case report: A 15 year old girl admitted to the ERwith diabetic ketoacidosis. She was diagnosed as neonatal diabetesat the age of 16 months and wasput on insulin therapy. Her parents arehealt...

Background: Hashimoto’s thyroiditis (HT) is considered the most common autoimmune disease and the predominant cause of hypothyroidism in iodine sufficient countries. HT may appear clinically in approximately 0.1–2% of the population.Aim: The study in hand aimed at assessing the role of thyroid ultrasonography in the diagnosis of HT patients discriminating them from other causes of hypothyroidism. A scoring system of sonographic findings was a...

Introduction: Fahr’s disease, is a rare neurological disorder characterized by abnormal calcified deposits in the basal ganglia with a prevalence of <1/1 000 000Case report: A 15-year-old male presented with focal seizures in right upper and lower limbs that progressed to generalized tonic clonic seizure and status epilepticus. No history of head trauma, central nervous system infection, stroke, hypertension, diabetes, or autoimmune disease No f...

Introduction: Thyroid storm is a rare complication of hyperthyroidism. In pregnant patients can cause spontaneous abortions, fetal demise. Aggressive treatment is needed.Case report: 26 years female 20 weeks pregnant; Graves’ disease for five years, was on carbimazole but she discontinued since she became pregnant Shortly after that, she started to complain with progressive dyspnea at less than ordinary effort, bilateral lower limb swelling, increas...

Introduction: Severe HTG usually occurs in a patient with genetic predisposition encoding various apolipoproteins (APOE, APOA5, APOC2, APOB), lipoprotein lipase (LPL), exacerbated by secondary factors as diabetes, obesity, high alcohol intake Case report: 35 yr old diabetic male presented with repeated vomiting with severe epigastric pain He had similar attack 1 year ago diagnosed as acute pancreatitis. 3 years ago he was diagnosed SLE with antiphospholi...

Background: Adrenocortical carcinomas (ACC) are rare malignancy with an incidence of 0.7-2 per million population per year. While ~60% of ACC are functional, clinical manifestations of hyper-secretion are seen in only ~40% of the cases. Here, we report a case of ACC with initial presentations of hypokalemia and hypertension mimicking hyperaldosteronismCase report: A 37 year old male complaining of generalized weakness of 2 years duration and fatigue with...