Endocrine Abstracts

Introduction: Malignant pheochromocytomas present a real challenge for practitioners. This entity of tumors is rare, with complex characterization, and heterogenocity in their evolution and prognosis. Given the rarity of this tumor group, there is no consensus on the therapeutic management. The management must be in a multidisciplinary framework. Through this illustrative case, we propose a literature review of this rare entity with discussion of the different therapeutic opti...

We present a case of a 56-year-old male who reported to us with history of instability of gait since one year which was acute in onset and progressive, there was also history of hearing impairment and constipation since 3 years without improvement despite several symptomatic treatments. There was no history of weakness in any part of body, headache, vomiting, convulsions or alteration of sensorium. There was no history of trauma to the head, fever or drug intake. On examinatio...

We report a case of small cell neuroendocrine carcinoma of laryngeal localization. The involvement of the larynx still exceptional. We present in this paper the radiological, pathological and therapeutic aspects of this tumor that was diagnosed in a 48-year-old man. A 59 years old male patient, chronic smoker, with 10 packs per year; without any particular medical history. he consulted for a rapidly progressive cervical swelling since one year, associated with dysphonia. The w...

Introduction: Pheochromocytoma is a rare tumor of chromaffin cells localized in the adrenal gland. It is responsible of secretion of catecholamines in a supra physiologic amount, leading to hypertension. Some patients may present with hypotension despite having high circulating levels of catecholamines. The challenge is to stabilize blood pressure by medication in cases with fluctuation of blood pressure.Case presentation: 49-year-old woman suffered from...

Introduction: Ganglioneuroma (GN) is a benign, well-differentiated nerve tumor composed of mature sympathetic ganglion cells and nerve fibers, and most commonly located in the posterior mediastinum and retroperitoneum. GN’s are rarely found in the adrenal gland. This tumor is usually asymptomatic and, in the majority of cases, detected incidentally. The diagnostic confirmation is histologic. We report a case of adrenal GN revealed by an adrenal incidentaloma.<p class=...

Introduction: Cushing’s syndrome (CS) is typically characterized by faciotronic obesity with signs of protein hypercatabolism, which may be iatrogenic or endogenous (adrenal or ATCH dependent). We report a case of CS of unusual presentation.Case Report: We report the case of a 45-year-old patient, referred for etiological assessment and management of an atypical cushing syndrome.– Symptomatology dates back to 2007, by the appearance of abdomina...

Introduction: Odontogenic facial cellulitis (OFC) is a soft cellulo fatty tissue infection of lesser resistance in different spaces, delimited by the musculoaponeurotic insertions on the maxillary and mandibular bone cortices. when patients have underlying diseases such as diabetes mellitus (DM) or cancer, compromised immune systems may lead to the opportunistic progression of seemingly minor infections. We report the case of a patient who presented an inaugural diabetic ketoa...

Introduction: Bardet-Biedl syndrome (BBS) is a rare disorder. It is an autosomal recessive hereditary ciliopathy, including: Multivisceral impairment, associated with obesity, learning disabilities, with or without intellectual deficit. We report the observation of 2 patients followed in our training for morbid obesity.Case Report: Case 1: O. Y. 17 years old, from a non-consanguineous marriage. Admitted for management of morbid obesity, BMI=70 kg/m2...

Introduction: Autoimmune polyendocrinopathy syndrome (APS) type 4 is rare, characterized by an association between an autoimmune endocrine disease with another endocrine or non-endocrine autoimmune disease, and this association cannot be attributed to APS type 2 or 3. We report the observations of 3 cases with APS type 4.Cases presentations: Case N 1:Patient 16 years old, type 1 diabetic for 9 years under insulin therapy, with...

Introduction: Excess weight has become a major public health problem. Type 2 diabetes and obesity are known risk factors for kidney disease. The aim of this study is to determine the effect of obesity on glomerular filtration rate (GFR) and microalbiminuria in patients with diabetes.Methods: This is a descriptive cross-sectional study conducted over three years in obese and type 2 diabetic patients hospitalized in the Endocrinology and Diabetology Depart...