Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep658 | Endocrine-related Cancer | ECE2023

Clear cell renal carcinoma synchronous with various endocrine pathologies

Petria Andreea Raluca , Lazar Diana-Georgiana , Elena Oros Sabina , Ioachim Dumitru , Ionut Constantin Teodor , Grigorie Daniel

Introduction: Clear cell renal carcinoma (ccRCC) is a subtype of renal cell carcinoma, the most frequent one (80%) and usually affecting only one kidney. It is twice as common in men than women between 50 to 70 years old. It can be associated with some genetic conditions that predispose patients to ccRCC, like Von Hipple-Lindau disease. Some clinical observations and molecular studies raised the hypothesis that RCC is a hormone−dependent tumor.Case...

ea0070ep270 | Endocrine-related Cancer | ECE2020

All with men 2A in one family?

Lazar Diana-Georgiana , Vasilescu Sorana L. , Elena Oros Sabina , Dumitrascu Anda , Smarandache Romeo , Caragheorgheopol Andra

Multiple endocrine neoplasya type 2 (MEN-2) is a rare hereditary complex disorder caused by a germline activating mutation of the RET proto-oncogene. The estimated prevalence is approximately 1:30.000. Three clinical forms have been described depending on the phenotype: MEN2A (80%), MEN2B and familial medullary thyroid carcinoma (MTC).Clinically, MEN2A present with MTC (80–100%), unilateral or bilateral pheocromocytoma (40%) and primary hyperparath...

ea0073ep149 | Pituitary and Neuroendocrinology | ECE2021

Apparently non secreting adenoma: a new challenge

Diana-Georgiana Lazar , Elena Oros Sabina , Dumitrascu Anda , Alexandrescu Daniela , Raluca Petria Andreea , Stoica Sergiu

IntroductionSilent corticotroph adenoma represent an uncommon subtype of nonfunctioning adenoma, immunoreactive for ACTH, without clinical or biochemical evidence of hypercortisolism and unclear pathogenesis. Usually, they present with local mass effect (visual deterioration being the most common) and endocrine dysfunctions. They carry a more aggressive behavior, particularly upon earlier recurrence.Case presentation<p class="a...

ea0090ep636 | Endocrine-related Cancer | ECE2023

MiNEN of the proximal colon – a strange case

Lazar Diana-Georgiana , Raluca Petria Andreea , Elena Oros Sabina , Dumitrascu Anda , Buduluca Larisa , Ionut Constantin Teodor , Grigore Iulia , Grigorie Daniel , Brezean Iulian , Dumitru Aldoescu Sorin , Degeratu Daniela

Introduction: Ectopic ACTH syndromes account for 5–10% of Cushing syndrome, with intrathoracic and gastrointestinal–pancreatic neuroendocrine tumors being the most common causes, followed by small cell lung cancer, adrenal paraganglioma and medullary thyroid carcinoma.Case report: A 50-year-old male hypertensive and diabetic patient was transferred to our clinic for emergency endocrine care for hypokalemia. He had mild hypercortisolism and live...