Endocrine Abstracts

Adrenocortical tumorigenesis has been observed in mice. It is speculated to be gonadotropin dependent. In particular LH receptors appear to be found within such adrenal tumors in high density and elevated LH levels may be related to adrenal tumorigenesis. The aim was to describe the case of a patient who after ovariectomy developed a large malignant adrenal tumor. A patient, female, aged 42 presented with uterine leiomyomas. She was treated by surgical excision of the uterus a...

Introduction: Patients with autoimmune diseases are known to develop other autoimmune conditions. Adrenal insufficiency of autoimmune etiology is known to coexist with autoimmune diabetes mellitus, Hashimoto’s thyroiditis and vitiligo. However, Graves’ disease in the context of adrenal insufficiency of autoimmune etiology is rare.Aim: The aim was to describe the case of a patient who presented with fatigue and was diagnosed to have hyperthyroid...

: Postmenopausal osteoporosis is a common condition affecting many women. Management of postmenopausal osteoporosis involves the administration of vitamin D, calcium and antiresorptive agents. The long-term management of postmenopausal osteoporosis with antiresorptive agents may present some dangers and adverse effects such as bone necrosis or atypical bone fractures.Case report: The aim was to describe the case of a female patient with postmenopausal ...

Introduction: Stress is a known risk factor for the development of Graves’ disease. We have previously described the role of bereavement as an inducing factor for Graves’ disease. Bereavement as an inducing factor for Graves’ disease was shown to affect primarily female patients after the loss of a loved one. However, it appears that other stressful life events may also cause Graves’ disease.Aim: The aim of the study was to describe t...

Introduction: Barrett’s esophagus is metaplasia in the cells of the lower end of the esophagus. It is characterized by the replacement of the normal stratified squamous epithelium lining of the esophagus by simple columnar epithelium with goblet cells. The disease is often related to gastroesophageal reflux and patients have pain necessitating chronic usage of proton pump inhibitors. Proton pump inhibitors have been associated with the development of low bone mineral dens...

Introduction: Adrenal myelolipoma is an extremely rare benign adrenal tumor. Adrenal myelolipoma is characterized by the presence within the adrenal gland of mature adipose tissue and active bone marrow elements. Owing to their non-functional nature most cases are incidental, either at autopsy or through computer tomography scan. Occasionally the lesions attain a large size to become clinically apparent. Seropositive rheumatoid arthritis is a disorder affecting approximately 1...

Introduction: Primary hyperparathyroidism is currently a frequent disorder. In the past primary hyperparathyroidism was diagnosed late in the course of the disease. With the introduction of routine calcium measurements, as well as the awareness of the disease amongst clinicians, the disorder is frequently recognized in asymptomatic patients. Thus, the clinical profile of primary hyperparathyroidism is changing.Aim: The aim was to describe the clinical pr...

Primary hyperparathyroidism is currently recognized with increasing frequency by routine calcium measurement in biochemical examinations. Primary hyperparathyroidism may be due to a parathyroid adenoma, parathyroid hyperplasia and, rarely, parathyroid carcinoma. Cinacalcet is used in the medical management of primary hyperparathyroidism.The aim was to assess the role of cinacalcet in the treatment of primary hyperparathyroidism.Pat...

Primary hyperparathyroidism is a rather frequent disorder characterized by high plasma PTH and calcium. Vitamin D deficiency is prevalent in all areas of the world. Vitamin D deficiency has been described in patients with primary hyperparathyroidism. When present, vitamin D deficiency may be associated with large size parathyroid adenomas and musculoskeletal pain.The aim was to describe two cases of primary hyperparathyroidism and vitamin D deficiency.</...

Acromegaly is known to be associated with increased cardiovascular risk. Additionally, acromegaly is known to be associated with disordered carbohydrate metabolism. Lipid levels in acromegaly have not been extensively studied. The aim was to study lipid levels in acromegaly.Methods: In 32 patients with newly diagnosed acromegaly lipid levels were studied. In particular total cholesterol, HDL cholesterol, LDL cholesterol and triglyceride levels were measu...