Searchable abstracts of presentations at key conferences in endocrinology

ea0025p346 | Thyroid | SFEBES2011

Changes in urinary fractional excretion (FE) of calcium and phosphate following treatment of hyperthyroid cats

Williams Tim , Elliott Jonathan , Syme Harriet

Hyperthyroid cats have elevated parathyroid hormone (PTH) concentrations and suppressed fibroblast growth factor-23 (FGF-23) concentrations, both of which normalise following treatment of hyperthyroidism. PTH, FGF-23, and thyroid hormone can influence the renal reabsorption of calcium and phosphate. The aim of the present study was to assess the influence of hyperthyroidism on renal tubular function in cats indirectly, by comparing the FE of electrolytes in hyperthyroid cats w...

ea0013p315 | Thyroid | SFEBES2007

Subclinical hyperthyroidism in cats

Wakeling Jennifer , Elliott Jonathan , Syme Harriet

Cats are the only species, other than humans, in which naturally occurring, non-malignant hyperthyroidism has been recorded. Feline hyperthyroidism has many similarities to toxic nodular goitre, including age at risk, presentation, histological features and similar ‘switch-on’ mutations of the TSH receptor and linked G-proteins. Subclinical hyperthyroidism is well recognised in humans but has only recently been described in cats. We present preliminary data from a pr...

ea0035p194 | Cardiovascular Endocrinology & Lipid Metabolism | ECE2014

Insulin dynamics and its associated signalling pathways in equids predisposed to laminitis

Timpson Amy , Elliott Jonathan , Harris Patricia , Mestre Amanda de , Menzies-Gow Nicola

Laminitis, an inflammatory condition of the sensitive and specialised architecture (the laminae) in the equine hoof, can be induced by over-ingestion of non-structural carbohydrates (NSC) from spring/summer pasture. Some equids that are predisposed to laminitis appear to share characteristics described in human patients with metabolic syndrome, such as vascular dysfunction, obesity, development of an inflammatory profile and insulin resistance. We investigated whether adipose ...

ea0035p195 | Cardiovascular Endocrinology & Lipid Metabolism | ECE2014

Laminitis: finding the key to predisposition of the metabolic disorder affecting the hoof in equids

Timpson Amy , Elliott Jonathan , Harris Patricia , Cheng Zhangrui , Rainbow Lucille , Mestre Amanda de , Menzies-Gow Nicola

Laminitis, an inflammatory condition of the sensitive and specialised architecture (the laminae) in the equine hoof, can be induced by over-ingestion of non-structural carbohydrates (NSC) from spring/summer pasture. Some equids that are predisposed to laminitis appear to share characteristics described in human patients with metabolic syndrome. We investigated if adipose tissue from laminitis prone equids (LP) functions differently from non-laminitis prone equids (NL), by exam...