Searchable abstracts of presentations at key conferences in endocrinology

ea0069p38 | Poster Presentations | SFENCC2020

Requirement of staged interventions in a complex case of Acromegaly and Obstructive Sleep Apnoea

Dhar Mili , Elias Jennifer , Field Benjamin , Zachariah Sunil , Emmanuel Julian

Section 1: Case history: We present the case of a 35-year-old gentleman referred by his GP to Endocrinology clinic for loss of libido and testosterone deficiency. His co-morbidities included obesity (BMI 59 kg/m2), hypertension and obstructive sleep apnoea (OSA) requiring overnight continuous positive airways pressure (CPAP) therapy. Routine pituitary profile showed luteinising hormone 4.8 IU/l (1–8), testosterone 7.1 nmol/l (8–25), prolactin 232 mU/l (86&...

ea0077cc1 | (1) | SFEBES2021

Cinacalcet in the Treatment of Malignancy-Related Hypercalcaemia: A Case Report

Smout Vera , Lakshmipathy Kavitha , Emmanuel Julian , Clark James , Field Ben , Nayyar Vidhu , Zachariah Sunil

Malignancy-related hypercalcaemia occurs in over 20% of cancer patients. Most cases are due to enhanced production of parathyroid hormone-related peptide (PTHrP) by tumours and carry a poor prognosis of survival of weeks to months. A 74 year old man with a history of prostate cancer treated with radical radiotherapy in 2013 and androgen blockade until 2015 underwent CT and PET/CT scans in 2017, which showed liver and spleen abnormalities, suggestive of metastases, but unlikely...

ea0077p98 | Neuroendocrinology and Pituitary | SFEBES2021

Hypopituitarism secondary to hydrocephalus associated with tectal plate tumour

Lakshmipathy Kavitha , Smout Vera , Emmanuel Julian , Nayyar Vidhu , Field Benjamin , Clark James , Zachariah Sunil

Case History: 17 year old boy presented with a six week history of polyuria, polydipsia, headaches and easy fatiguability. Further investigations confirmed hypopituitarism with low early morning urine osmolality. MRI brain revealed soft tissue mass arising from tectal plate extending into cerebral aqueduct resulting in hydrocephalus with normal pituitary gland. Hydrocortisone, Levothyroxine and Desmopressin were started and urgent in-patient transfer to Neurosurgical unit in t...

ea0069p39 | Poster Presentations | SFENCC2020

Primary hyperparathyroidism in pregnancy: Uncommon manifestation of significant weight loss

Varga Timea , Kurera Isuri , Clark James , Field Benjamin , Nayyar Vidhu , Emmanuel Julian , Zachariah Sunil

Section 1&2: Case history and investigations: Primary hyperparathyroidism is a rare condition in pregnancy. The occurrence rate is about 1 % and up to 80 % of the patients are asymptomatic. Clinical symptoms are nonspecific. However, severe maternal, foetal and neonatal complications including neonatal death have been reported in literature. 27 years old Asian lady presented to Emergency Department with abdominal pain in July 2019. She was found to have raised calcium at l...

ea0074ncc54 | Highlighted Cases | SFENCC2021

Surgical dilemma in management of hyperparathyroidism in multiple endocrine neoplasia type 1

Smout Vera , Lakshmipathy Kavitha , Emmanuel Julian , Nayyar Vidhu , Field Ben , Clark James , Bano Gul , Zachariah Sunil

Case History: 29 year old lady presented with profuse diarrhoea, lethargy and hypokalaemia in 2010. CT scan confirmed mass lesion in tail of pancreas. Chromogranin A and 24 hour urinary 5HIAA were normal. Fasting Gut hormone level showed elevated level of Vasoactive Intestinal Peptide (VIP), suggesting diagnosis of VIPoma. Further investigations confirmed hyperparathyroidism and microprolactinoma. Investigations: Adjusted calcium 2.98 mmol/l (<2.55), ...