Searchable abstracts of presentations at key conferences in endocrinology

ea0056gp248 | Thyroid non cancer | ECE2018

Thyroid function in early-treated adult PKU patients

Sumanszki Csaba , Kiss Erika , Simon Erika , Patocs Attilla , Nagy Endre

Introduction: Phenylketonuria (PKU) is a rare inherited metabolic disorder that leads to the toxic accumulation of phenylalanine (Phe) causing usually severe mental retardation and seizures. The basis of the lifelong therapy is low in natural-protein diet and Phe-free amino acid mixtures, that provide the daily necessary amino acids, vitamins and micronutrients, such as Iodine and Selenium. It is not well known, whether the adherence to the therapy can influence the thyroid fu...

ea0063p781 | Thyroid 2 | ECE2019

Iodine and selenium status in adult PKU

Sumanszki Csaba , Kiss Erika , Simon Erika , Galgoczi Erika , Soos Aron , Patocs Attila , Kovacs Bela , Nagy Endre V , Reismann Peter

Background: The standard, lifelong therapy of phenylketonuria (PKU) is natural protein-restricted diet completed with Phenylalanine (Phe)-free L-amino acid mixtures that provide the daily necessary micronutrients, such as iodine and selenium. Our main objective in this study was to assess the iodine and selenium status of patients with PKU, based on their adherence to the low-Phe diet, compared to a healthy control group. Secondly, we aimed to asses whether adherence to therap...