Searchable abstracts of presentations at key conferences in endocrinology

ea0014p557 | (1) | ECE2007

Comparative analysis of reactivity of macroprolactin in first and second-generation prolactin assays

Rigó Erzsébet , Toldy Erzsébet , Löcsei Zoltán , Toldy Erzsébet , Szabolcs István , Kovács Gábor L.

Issue: Macroprolactin (MPRL) is a high molecular mass complex of prolactin with minimal bioactivity in vivo that may be the cause of elevated serum prolactin (PRL) as determined by immunoassay. Unrecognised macroprolactinemia can lead to misdiagnosis and mistreatment. The frequency of MPRL is highly dependent on the affinity of the antibody used in the assay.The aim of this study: Was to compare the frequency and quantity of MPRL measured by a first and ...

ea0014p141 | (1) | ECE2007

Thyroglobulin-antibodies in the “normal” range may decrease the diagnostic accuracy of thyroglobulin in the care of patients with differentiated thyroid cancer

Zoltán Locsei , Erzsébet Toldy , István Szabolcs , Gábor Kovács L.

Issue: The use of thyroglobulin (Tg) as tumor marker in differentiated thyroid cancer (DTC) is limited in the presence of thyroglobulin-antibodies (TgAb) but it is generally believed that this is true only for TgAb concentrations over the normal ‘cut off’ point.The aim: Of this study was to investigate if TgAb-s in the normal range, considered to be physiological, may also influence the accuracy and clinical relevance of Tg measurement.<p c...

ea0070aep149 | Bone and Calcium | ECE2020

Investigation of total- and free-25OHD levels by different methods in pregnant women

Tüttő Ágnes , Balázs Karvaly Gellért , Gerszi Dóra , Várbiró Szabolcs , Lőcsei Zoltán , Konderak Judit , Toldy Erzsébet

Avoiding vitamin D deficiency can be beneficial in prevention of adverse maternal, fetal and neonatal outcomes. Because of increasing level of vitamin D-binding protein (DBP) in pregnancy, the determination of free-25OHD should be required, whose adequate measure is a challenge for the analytics. Literature data are contradictory whether total-or free-25OHD fraction is more reliable taking into consideration the methods of measurement. Data of publications on free or total, bi...

ea0070aep150 | Bone and Calcium | ECE2020

Analysis of 25OHD levels in chronic renal failure depending on the methods

Toldy Erzsébet , Konderak Judit , Kovács László , Tüttő Ágnes , Balázs Karvaly Gellért , Lőcsei Zoltán

Vitamin D deficiency is common in patients with chronic renal failure (CRF) based on routinely determined total-25-hydroxyvitaminD (t-25OHD) levels. The present knowledge is contradictory whether the direct measured free-25OHD (dm_f-25OHD) or the calculated free-25OHD (c_f-25OHD) is the best indicator of the vitamin D supply for CRF patients. Adding methods to our previously described first experiences on this subject, in this study we aimed to serve newer data to make this qu...

ea0014p420 | (1) | ECE2007

Changes of bone metabolism at the onset of puberty

Csákváry Violetta , Toldy Erzsébet , Puskás Tamás , Kovács Gábor L. , Oroszlán György

Object: Adolescence is the period during which the greatest accrual of bone mineral occurs. During puberty, changes of bone metabolism primarily depend on maturity. Diagnosis and therapy of childhood bone diseases is difficult due to the lack of reference ranges of metabolic bone markers. Our aim was to establish the reference values of bone markers in primary school students (mean age: 13.2±1.2 years; 65 girls, 56 boys).Methods: The children were d...