Searchable abstracts of presentations at key conferences in endocrinology

ea0016p572 | Obesity | ECE2008

Activated protein C levels in obesity and weight loss influence

Sola Eva , Espana Francisco , Vaya Amparo , Estelles Amparo , Garcia Katherinne , Hernandez-Mijares Antonio

Introduction: Several haemostatic disturbances have been described in obese patients. Nevertheless, the state of coagulation inhibitors has been scarcely studied in these patients. Activated protein C (APC) is the anticoagulant enzyme formed upon activation of the protein C (PC) by the thrombin-thrombomodulin complex on the surface of endothelial cells. Morbid obesity is associated to endothelial dysfunction, which could cause a reduction in APC generation.<p class="abstex...