Searchable abstracts of presentations at key conferences in endocrinology

ea0035p842 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Clinical evaluation of follow-up of 62 patients: do treatment methods in acromegaly affect the rates of cure and hypophyseal insufficiency?

Evran Mehtap , Sert Murat , Tetiker Tamer

Background: Transsphenoidal surgery of pituitary adenoma is often first-line therapy for patients with acromegaly. Pharmacotherapy and/or radiotherapy are applied when surgery fails to achieve good disease control, or when surgery is impossible or contraindicated. In this study, we report the results of therapies, rates of cure and hypophyseal insufficiency in our acromegalic patients.Methods and results: Medical files of the 62 patients who were followe...

ea0049ep1241 | Thyroid (non-cancer) | ECE2017

Two pseudomalabsorbtion cases successfully treated with parenteral levothyroxine

Altuntaş Seher Cetinkaya , Evran Mehtap , Sert Murat , Tetiker Tamer

Hypothyroidism is a common endocrine disorder which is easily treatable by an appropriate thyroid hormone replacement therapy in the majority of patients. In some patients, hypothyroidism is refractory to oral levothyroxine substitution. Common causes of lack of response to levothyroxine replacement comprise non-compliance and impaired absorption. We report a case of pseudomalabsorption of levothyroxine. Here, we report two female patients with hypothyroidism who had multinod&...

ea0041ep18 | Adrenal cortex (to include Cushing's) | ECE2016

Carotid intima-media thickness as the cardiometabolic risk indicator in patients with nonfunctional adrenal mass and metabolic syndrome screening

Akkus Gamze , Tetiker Tamer , Deniz Ali , Evran Mehtap , Sert Murat

Objective: Nonfunctional adrenal masses are a risk indicator of increased cardiometabolic risk. Especially; increased thrombogenic ambient, insulin resistance, hepatosteatosis and abdominal obesity are determined in these patients with nonfunctional adrenal masses. Our purpose was to show the association of adrenal incidentalome and metabolic syndrome in consideration of the studies and to detect the increase in the carotid intima-media thickness which is regarded as the prece...

ea0037ep31 | Adrenal cortex | ECE2015

A case of aldosterone-secreting giant adrenal carcinoma: a case report

Evran Mehtap , Akkus Gamze , Sert Murat , Tetiker Tamer

Introduction: Primary aldosteronism is presented with signs of hypertension and hypokalaemia classically, however, primary adrenal carcinoma is very rare condition. We aimed to present a patient with a metastatic adrenal carcinoma after the primary diagnosis of hyperaldosteronism.Case report: A 46 years old male patient was referred to our hospital with weakness, dry mouth and weight loss. He had lost weight as 31 pounds during last 3 months. Physical ex...

ea0037ep1183 | Clinical Cases–Pituitary/Adrenal | ECE2015

Laryngeal carcinoma in acromegalic patients: a rare case

Akkus Gamze , Evran Mehtap , Sert Murat , Tetiker Tamer

Introduction: Acromegaly is a very rare disease with persistent GH secretion due to excessive release of liver IGF1. The risk of malignancy, particularly colon cancer, is increased in acromegalic patients. But no evidence is found in the literature associated increasing of laryngeal carcinoma in acromegalic patients. We aimed to present this case that laryngeal carcinoma should be considered in acromegaly by the clinicians.Case report: A 51-year-old male...

ea0035p841 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Demographical and clinical characteristics of 62 acromegalic patients

Evran Mehtap , Sariakcali Baris , Sert Murat , Tetiker Tamer

Background: Acromegaly is a relatively rare endocrine disorder which may result in morbidity and mortality. In this study, we report the demographical and clinical characteristics of 62 acromegalic patients who were followed-up at our Department of Endocrinology Clinic.Methods and results: In this retro-prospective study, medical files of the patients who were followed-up from 1984 to 2013 were examined. Data was obtained for age at the time of diagnosis...

ea0070aep762 | Pituitary and Neuroendocrinology | ECE2020

Immunohistochemical subtypes of growth hormone-secreted pituitary adenoma and relationship with the clinical course and seconder malignancy

Akkus Gamze , Cetinalp Ralp , Bagir Emine , Evran Mehtap , Sengoz Sinem , Zorludemir Suzan , Sert Murat , Tetiker Tamer

Purpose: Most of the acromegaly cases are due to agrowth hormone-secreting pituitary adenomas of which immunohistochemical subtype seperated as sparsely granulated adenoma (SGA) and densely granulated adenoma (DGA). SGA’s were reported to have more aggressive clinical course and therapy resistance. We investigated our patients for these aspects.Method: Forty (F21, M19) patients with acromegaly who diagnosed and operated for pituitary adenoma at our...

ea0070ep201 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Hospitalization cost of diabetic foot ulcerations treated by multidisciplinary team in clinical practice: A restrospective study from Southern Turkey

Evran Mehtap , Karagün Bariș , Akkus Gamze , Sert Murat , Tetiker Tamer

Purpose: Diabetic Foot Ulceration (DFU) is common problem throughout the world and resulting in major economic consequences for the patients and country. We aim to describe estimated cost of illness between patients with DFU in southern Turkey.Methods: A total of 148 (F = 55, M = 93) patients with DFU were included in this retrospective study. We also included more than one admission of the patients with DFU. Patients characteri...

ea0070aep598 | Pituitary and Neuroendocrinology | ECE2020

The importance of DHEA-S levels in cushing’s syndrome; is there a cut-off value in the differential diagnosis?

Ciftci Dogansen Sema , Soyluk Selcukbiricik Ozlem , Selek Alev , Erol Selvinaz , Hekimsoy Zeliha , Esen Pazir Ayse , Dursun Huseyin , Sahin Serdar , Oruk Gonca , Mert Meral , Soylu Hüseyin , Sarer Yurekli Banu , Eda Ertorer Melek , Omma Tülay , Evran Mehtap , Adaș Mine , Tanrikulu Seher , Aydin Kadriye , Pekkolay Zafer , Can Bulent , Karakilic Ersen , Karaca Zuleyha , Bilen Habib , Canturk Zeynep , Cetinarslan Berrin , Kadioglu Pinar , Yarman Sema

Purpose: To evaluate the relationship between basal dehydroepiandrosterone-sulfate (DHEA-S) levels and other tests used in the diagnosis and differential diagnosis of Cushing’s Syndrome (CS) among the patients with pathologically confirmed CS.Methods: In this multicenter study, the data of 623 patients with CS were evaluated retrospectively. The patients were classified as Group 1 (n = 353 Cushing’s disease;CD), Group 2 (n</e...