ea0007s30 | Molecular basis of thyroid disease | BES2004
, Knauf J
, Croyle M
, Nikiforov Y
, Mitsutake N
Recent advances in treatment of chronic myelogenous leukemia and gastrointestinal stromal tumors with selective tyrosine kinase inhibitors have generated interest in identifying other cancers that could be approached with similar strategies. Cancers derived from follicular (papillary thyroid cancer; PTC) and parafollicular thyroid C cells (medullary thyroid cancer; MTC) represent paradigms of solid neoplasms in which tumor initiation events are well defined, and involve activa...