Searchable abstracts of presentations at key conferences in endocrinology

ea0075d12 | Diabetes | EYES2021

Sex differences in quality of life and sexual function in type 2 diabetes mellitus: results from the RECOGITO trial

Feola Tiziana , Ferrari Davide , Pofi Riccardo , Lecis Claudio , Centello Roberta , Lenzi Andrea , Gianfrilli Daniele , Isidori Andrea M. , Giannetta Elisa

Background: Type 2 diabetes mellitus (T2DM) significantly impacts Health-Related Quality of Life (HRQoL) and sexual function. The aim of this study was to evaluate sex differences in HRQoL and sexual function in patients with T2DM.Methods: We performed an ancillary study of RECOGITO trial (REmodelling in Diabetic CardiOmyopathy: Gender Response to PDE5i InhibiTOrs - NCT01803828). All patients completed the 36-item-Short-Form Health Survey (SF-36), assess...

ea0081p280 | Adrenal and Cardiovascular Endocrinology | ECE2022

Coagulation parameters in asymptomatic patients with adrenal incidentaloma: is mild autonomous cortisol secretion correlated with thromboembolic risk?

Minnetti Marianna , Bonaventura Ilaria , Hasenmajer Valeria , De Alcubierre Dario , Tomaselli Alessandra , Ferrari Davide , Pofi Riccardo , Cozzolino Alessia , Sbardella Emilia , Lenzi Andrea , Isidori Andrea

Background: Overt hypercortisolism is highly associated with venous thromboembolism. Patients with CushingÂ’s syndrome (CS) typically show an alteration of the intrinsic coagulation pathway, especially an increase in factor VIII (f-VIII), and increased levels of coagulation inhibitors (i.e., antithrombin III) as a compensatory response. Mild autonomous cortisol secretion (MACS) has been variably associated with higher risk of cardiovascular events and mortality compared to...

ea0014p130 | (1) | ECE2007

Enhanced expression of functional P2X7 receptor in human papillary thyroid cancer

Dardano Angela , Ferrari Davide , Cuccato Sabina , Santini Eleonora , Caraccio Nadia , Gulinelli Sara , Callegari Giulia , Faviana Pinuccia , Solini Anna , Di Virgilio Francesco , Monzani Fabio

Extracellular ATP modulates several biological processes via activation of plasma membrane receptors (P2Rs) in normal human thyrocytes (NT). We characterized P2Rs expression and function in two thyroid cancer cell lines: FB1 (anaplastic cancer) and FB2 [papillary cancer (PTC)]. P2Rs expression was evaluated by RT-PCR and WB, intracellular Ca2+changes by fluorimetric technique (Fura2-AM), IL-6 release by ELISA, intracellular [i(ATP)] and extracellular ATP [...