ea0056ep115 | Pituitary and Neuroendocrinology | ECE2018
, Cunha Filipe
, Ferreira Ivan
, Mesquita Joana
Introduction: Hyperprolactinemia is associated with suppression of the hypothalamic-pituitary-gonadal axis and its a frequent cause of infertility, occurring in about 3040% of infertile women. The bioactive fraction of prolactin is a 23-kDa monomer. However, there are other isoforms with reduced or absent bioactivity, such as macroprolactin, which can be detected by the precipitation reaction by polyethylene glycol. Macroprolactinemia should be suspected in the pre...