Searchable abstracts of presentations at key conferences in endocrinology

ea0016p108 | Clinical cases | ECE2008

Prolonged QT interval on the electrocardiogram in hypogonadal men

Filippini Barbara , Giraldi Francesca Pecori , Toja Paola Maria , Michalidis Jorgo , Badiale Marco Stramba , Cavagnini Francesco

Background: QT interval reflects cardiac ventricular repolarization and, if prolonged, increases the risk of malignant arrhythmias such as torsade de pointes. QT interval duration is similar in boys and girls during childhood but shortens in males after puberty. In fact, reference limits for QTc in adults reflect this difference, i.e. lower than 460 ms in women and lower than 440 ms in men. Experimental studies suggest that testosterone is the major contributor to shortening o...

ea0022p561 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

The diagnosis of GH deficiency in obese patients: what help from pharmacological blockade of lipolysis?

Orsini Federica , Cattaneo Agnese , Grasso Alice , Filippini Barbara , Fatti Maria Letizia , Moro Mirella , Scacchi Massimo , Cavagnini Francesco

The diagnostic approach to GH deficiency (GHD) in obese patients is complicated by the reduced spontaneous and stimulated GH secretion associated with overweight. A GH response to GHRH+arginine lower than 4.2 μg/l is currently considered indicative of GHD in obesity (Corneli et al., Eur J Endocrinol 2005). Aim of the study was to verify the diagnostic validity of this cut-off value by investigating the effect of acute pharmacological blockade of lipolysis on...