Searchable abstracts of presentations at key conferences in endocrinology

ea0011p912 | Thyroid | ECE2006

Is 131I therapy for hyperthyroidism harmful for testis function?

Ceccarelli C , Canale D , Fiore E , Moschini C , Caglieresi C , Vitti P , Pinchera A

Radioiodine-131 is commonly used for treatment of hyperthyroidism, however the effects on testis function are not known. This prompted us to study testis function in hyperthyroid men after 131I treatment. 15 hyperthyroid patients scheduled for 131I treatment underwent: testis US, hormone assessment and sperm analysis before and 45 days, 3, 6 and 10–15 months after 131I. The control group (for testis volume and semen analysis) was constitut...

ea0029p787 | Endocrine tumours and neoplasia | ICEECE2012

Expression of a novel isoform of thyroid peroxidase (TPO) gene in breast cancer (BC)

Muller I. , Giani C. , Fiore E. , Belardi V. , Sabatini S. , Rosellini V. , Funel N. , Campani D. , Grennan-Jones F. , Zhang L. , Lewis M. , Bakhsh A. , Roncella M. , Ghilli M. , Pinchera A. , Vitti P. , Dayan C. , Ludgate M.

Introduction: BC patients have a high prevalence of anti-TPO-autoantibodies (TPOAb), which seem to be protective in BC patients. We hypothesized the presence of T-lymphocytes citotoxicity against a common antigen between thyroid and BC cells.Aim: To evaluate the possible expression of TPO gene in BC.Materials: Frozen tissue specimens: 8 BC, 5 peri-tumoral breast tissues (PT), 3 pancreatic adenocarcinoma (P), 2 kidney cancers (K) an...