Searchable abstracts of presentations at key conferences in endocrinology

ea0059p165 | Obesity & metabolism | SFEBES2018

Obesity and diabetes in adults with down syndrome: data from a large diabetes centre in the United Arab Emirates (UAE)

Fojas Esphie , Moriarty Maura , Lessan Nader , Barakat Maha T

Background: Down Syndrome (DS) is the most common chromosomal abnormality. Obesity and type 1 diabetes mellitus (T1DM) are known to be more prevalent in patients with DS than the general population. Available data on the prevalence of type 2 diabetes mellitus (T2DM) in DS is scant.Objectives: This study aims to investigate the prevalence of obesity and diabetes mellitus (DM) in adults with DS seen in Imperial College London Diabetes Centre (ICLDC) in the...

ea0081ep403 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Covid-19 infection in an individual with Down Syndrome, obesity, and hypothyroidism: a case from the UAE

Grace Fojas Esphie , Al Shamsi Shamma , Salah Noshi Mohamed , Ali Tomader , Lessan Nader

Covid-19 infection severity has been associated with pre-existing conditions including obesity. Individuals with Down Syndrome (DS) are potentially at high risk. Reports on the outcomes of Covid-19 infection in individuals with DS are scant. Here we present such a case. MA is a 27-year old Emirati male with DS, obesity and hypothyroidism. He was brought to the ER with a history of hemoptysis (2 days), fever and cough (1 week). He tested positive for Covid-19. Initial investiga...

ea0065p216 | Metabolism and Obesity | SFEBES2019

Risk of sleep apnoea among Emirati patients with type 2 diabetes

Hassan Sama , Buckley Adam , Al Tameemi T , Fojas Esphie Grace , Barakat Maha T , Lessan Nader

Background: Type 2 diabetes (T2D) and obesity have been linked with sleeping disorders in general and obstructive sleep apnoea (OSA) in particular; both are highly prevalent amongst Emirati patients. However, little information is available in this population regarding the prevalence and symptomatology of OSA, its relationships with T2D and obesity, and its impact on health outcomes.Objectives: This study aims to investigate the risk of OSA based on the ...

ea0065p227 | Metabolism and Obesity | SFEBES2019

Bariatric surgery outcomes in super obese Emirati patients

Radha Saradalekshmi Koramannil , Fojas Esphie Grace , Barakat Maha T , Lessan Nader

Background: Efficacy of bariatric surgery (BS) in obesity management is well-established. The super-obese (BMI >50 kg/m2) as a subgroup may have specific phenotypic and genotypic characteristics. Prevalence of complications and risks of interventions may also be different in this group.Aims: We have investigated BS outcomes and compared effects of different operations among the superobese in an Emirati population.Methods...

ea0073aep164 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

The short-term effect of surgical and pharmacological intervention in obesity caused by MC4R deficiency: A single centre experience

Radha Saradalekshmi Koramannil , Fojas Esphie Grace , Ali Tomader , Suliman Sara GI , Lessan Nader

IntroductionMelanocortin-4-receptor (MC4R) deficiency is the commonest of the rare monogenic forms of obesity. Bariatric surgery (BS) is the most efficacious treatment modality in the more ’common’ polygenic obesity. Effect of surgical and drug treatment in obesity due to MC4R deficiency is not well-established.AimWe aimed to explore the effects of BS and drug treatment among the confirmed cases of ...