Searchable abstracts of presentations at key conferences in endocrinology

ea0013p268 | Steroids | SFEBES2007

A case of “cured” late-onset congenital adrenal hyperplasia

Fountain Annabel , Johnston Colin

We present a 46 year old female referred in 1990 with hirsutism, hypertension and irregular menses. She was not overweight at 50.3 kg. The facial hair was controlled with electrolysis; blood pressure controlled with Enalapril and Bendrofluazide.Initial biochemistry showed an elevated LH/FSH ratio (19.6:4.2 U/L), raised testosterone (3.9 nmol/L), high DHEA (14.7 umol/L) SynACTHen test revealed a significant increase in 17-hydroxyprogesterone basal 3.9 nmo...

ea0018p10 | (1) | MES2008

Positive correlation between radioisotope and CT/MRI imaging techniques in functioning adrenal adenomas may obviate the need for invasive adrenal vein sampling

Fountain Annabel , Vaks Vladimir , Wren Alison

A 48-year-old Afro-Caribbean female was referred from Accident & Emergency in December 2007 with low serum potassium. She had been diagnosed elsewhere with hypertension due to primary aldosteronism at the age of 28 but was then lost to Endocrine follow-up. She reported intolerance to spironolactone – blood pressure was controlled with Amiloride until 1999 and then Amlodipine. Questioning in clinic, January 2008, revealed that she had had extensive investigations when ...

ea0018p8 | (1) | MES2008

Clinical diagnosis of phaeochromocytoma leads to correct perioperative management despite negative biochemical and functional investigations

Fountain Annabel , Todd Jeannie , Meeran Karim , Palazzo Fausto , Robinson Stephen

We present a 44-year-old female referred to us with a two year history of episodic palpitations, chest tightness, headaches and pallor associated with hypertension. She had previously been extensively investigated by neurologists and cardiologists including MRI of the brain, renal ultrasonography, 24 h tape and echocardiography – all normal. Given the history, a CT of the adrenals was performed in 2007 which revealed a 1.5 cm nodule in the right adrenal with abnormal enha...

ea0015p275 | Pituitary | SFEBES2008

Isolated growth hormone deficiency with anterior pituitary hypoplasia and undescended posterior pituitary

Treibel Thomas A , De Silva Akila , Fountain Annabel EC , Wong Justin , Kaushal Rashmi

We describe the case of an Asian male who is currently 20 years of age. He originally presented aged 18 months with short stature (height below 3rd centile). Isolated growth hormone (GH) deficiency was confirmed by an insulin tolerance test (normal thyroid function/cortisol/GH antibodies). He commenced GH injections (1 unit/day), to which he responded well, reaching the 50th centile for height within one year. Due to his parents’ wishes, GH therapy was discontinued at 3 y...

ea0018oc4 | (1) | MES2008

MEN1: the full house

McGowan Barbara , Fountain Annabel , Chaudhri Owais , Mehta Puja , Tan Tricia , Hatfield Emma , Martin Niamh , Todd Jeannie , Meeran Karim

This gentleman was diagnosed with hyperparathyroidism at the age of 34 and was found to have multiple manifestations of MEN1.Hyperparathyroidism: He was diagnosed with hyperparathyroidism and underwent a parathyroidectomy with removal of 2 glands. Four years later calcium levels were raised once again and two further hyperplastic glands were removed, with cure of his hypercalcaemia.Gastrinoma and other pancreatic islet cell tumours...