Searchable abstracts of presentations at key conferences in endocrinology

ea0011p842 | Thyroid | ECE2006

Differential regulation of soluble Fas in patients with autoimmune thyroid disease

Fountoulakis S , Kolaitis N , Philippou G , Vartholomatos G , Tsatsoulis A

Introduction-objective: Fas-mediated thyroid cell apoptosis is differentially regulated in autoimmune thyroid disease (AITD) being up-regulated in Hashimoto’s thyroiditis (HT) and down-regulated in Graves’ disease (GD). The soluble form of Fas (sFas), lacking the transmembrane domain due to alternative splicing may inhibit apoptosis by binding to Fas ligand. In this preliminary study we examined whether sFas is also differentially expressed in patients with AITD....

ea0029p58 | Adrenal cortex | ICEECE2012

Treatment with mineralocorticoid receptor antagonists in ‘subclinical’ cases with adrenal adenomas and autonomous aldosterone secretion

Papanastasiou L. , Pappa T. , Tsounas P. , Tsiavos V. , Markou A. , Tseniklidi E. , Anastasakou M. , Fountoulakis S. , Prevoli A. , Piaditis G.

Introduction: Patients with adrenal adenomas appear to exhibit an appreciable prevalence of autonomous aldosterone secretion (AAS). Our aim was to evaluate the anti-hypertensive effect of targeted therapy with mineralocorticoid receptor (MR) antagonists in AAS patients.Patients and methods: We studied 60 hypertensive patients, 21 males and 39 females, harboring an adrenal adenoma with AAS. All patients were receiving combination of anti-hypertensive trea...